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Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes.
Kwak SH, Hernandez-Cancela RB, DiCorpo DA, Condon DE, Merino J, Wu P, Brody JA, Yao J, Guo X, Ahmadizar F, Meyer M, Sincan M, Mercader JM, Lee S, Haessler J, Vy HMT, Lin Z, Armstrong ND, Gu S, Tsao NL, Lange LA, Wang N, Wiggins KL, Trompet S, Liu S, Loos RJF, Judy R, Schroeder PH, Hasbani NR, Bos MM, Morrison AC, Jackson RD, Reiner AP, Manson JE, Chaudhary NS, Carmichael LK, Chen YI, Taylor KD, Ghanbari M, van Meurs J, Pitsillides AN, Psaty BM, Noordam R, Do R, Park KS, Jukema JW, Kavousi M, Correa A, Rich SS, Damrauer SM, Hajek C, Cho NH, Irvin MR, Pankow JS, Nadkarni GN, Sladek R, Goodarzi MO, Florez JC, Chasman DI, Heckbert SR, Kooperberg C, Dupuis J, Malhotra R, de Vries PS, Liu CT, Rotter JI, Meigs JB; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Kwak SH, et al. Among authors: haessler j. Diabetes Care. 2024 Jun 1;47(6):1042-1047. doi: 10.2337/dc23-2274. Diabetes Care. 2024. PMID: 38652672
Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations.
Lundin JI, Peters U, Hu Y, Ammous F, Avery CL, Benjamin EJ, Bis JC, Brody JA, Carlson C, Cushman M, Gignoux C, Guo X, Haessler J, Haiman C, Joehanes R, Kasela S, Kenny E, Lapalainien T, Levy D, Liu C, Liu Y, Loos RJF, Lu A, Matise T, North KE, Park SL, Ratliff SM, Reiner A, Rich SS, Rotter JI, Smith JA, Sotoodehnia N, Tracy R, Van den Berg D, Xu H, Ye T, Zhao W, Raffield LM, Kooperberg C; PAGE Study. Lundin JI, et al. Among authors: haessler j. Epigenetics. 2024 Dec;19(1):2333668. doi: 10.1080/15592294.2024.2333668. Epub 2024 Apr 3. Epigenetics. 2024. PMID: 38571307 Free PMC article.
Targeted Proteomics Reveals Functional Targets for Early Diabetes Susceptibility in Young Adults.
Shah RV, Zhong J, Massier L, Tanriverdi K, Hwang SJ, Haessler J, Nayor M, Zhao S, Perry AS, Wilkins JT, Shadyab AH, Manson JE, Martin L, Levy D, Kooperberg C, Freedman JE, Rydén M, Murthy VL. Shah RV, et al. Among authors: haessler j. Circ Genom Precis Med. 2024 Feb;17(1):e004192. doi: 10.1161/CIRCGEN.123.004192. Epub 2024 Feb 7. Circ Genom Precis Med. 2024. PMID: 38323454
Evidence of survival bias in the association between APOE-ϵ4 and age of ischemic stroke onset.
von Berg J, McArdle PF, Häppölä P, Haessler J, Kooperberg C, Lemmens R, Pezzini A, Thijs V; SiGN, FinnGen, Women’s Health Initiative; Pulit SL, Kittner SJ, Mitchell BD, de Ridder J, van der Laan SW. von Berg J, et al. Among authors: haessler j. medRxiv [Preprint]. 2023 Dec 1:2023.12.01.23294385. doi: 10.1101/2023.12.01.23294385. medRxiv. 2023. PMID: 38076909 Free PMC article. Preprint.
Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics.
Chan TF, Rui X, Conti DV, Fornage M, Graff M, Haessler J, Haiman C, Highland HM, Jung SY, Kenny EE, Kooperberg C, Le Marchand L, North KE, Tao R, Wojcik G, Gignoux CR; PAGE Consortium; Chiang CWK, Mancuso N. Chan TF, et al. Among authors: haessler j. Am J Hum Genet. 2023 Nov 2;110(11):1853-1862. doi: 10.1016/j.ajhg.2023.09.012. Epub 2023 Oct 23. Am J Hum Genet. 2023. PMID: 37875120 Free PMC article.
Author Correction: Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations.
Feofanova EV, Brown MR, Alkis T, Manuel AM, Li X, Tahir UA, Li Z, Mendez KM, Kelly RS, Qi Q, Chen H, Larson MG, Lemaitre RN, Morrison AC, Grieser C, Wong KE, Gerszten RE, Zhao Z, Lasky-Su J; NHLBI Trans-Omics for Precision Medicine (TOPMed); Yu B. Feofanova EV, et al. Nat Commun. 2023 Oct 19;14(1):6611. doi: 10.1038/s41467-023-42472-3. Nat Commun. 2023. PMID: 37857625 Free PMC article. No abstract available.
A Type 1 Diabetes Polygenic Score Is Not Associated With Prevalent Type 2 Diabetes in Large Population Studies.
Srinivasan S, Wu P, Mercader JM, Udler MS, Porneala BC, Bartz TM, Floyd JS, Sitlani C, Guo X, Haessler J, Kooperberg C, Liu J, Ahmad S, van Duijn C, Liu CT, Goodarzi MO, Florez JC, Meigs JB, Rotter JI, Rich SS, Dupuis J, Leong A. Srinivasan S, et al. Among authors: haessler j. J Endocr Soc. 2023 Oct 5;7(11):bvad123. doi: 10.1210/jendso/bvad123. eCollection 2023 Oct 9. J Endocr Soc. 2023. PMID: 37841955 Free PMC article.
Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk.
Liu X, Sun X, Zhang Y, Jiang W, Lai M, Wiggins KL, Raffield LM, Bielak LF, Zhao W, Pitsillides A, Haessler J, Zheng Y, Blackwell TW, Yao J, Guo X, Qian Y, Thyagarajan B, Pankratz N, Rich SS, Taylor KD, Peyser PA, Heckbert SR, Seshadri S, Boerwinkle E, Grove ML, Larson NB, Smith JA, Vasan RS, Fitzpatrick AL, Fornage M, Ding J, Carson AP, Abecasis G, Dupuis J, Reiner A, Kooperberg C, Hou L, Psaty BM, Wilson JG, Levy D, Rotter JI, Bis JC; TOPMed mtDNA Working Group in NHLBI Trans‐Omics for Precision Medicine (TOPMed) Consortium; Satizabal CL, Arking DE, Liu C. Liu X, et al. Among authors: haessler j. J Am Heart Assoc. 2023 Oct 17;12(20):e029090. doi: 10.1161/JAHA.122.029090. Epub 2023 Oct 7. J Am Heart Assoc. 2023. PMID: 37804200 Free PMC article.
Ancestral diversity in lipoprotein(a) studies helps address evidence gaps.
Lee MP, Dimos SF, Raffield LM, Wang Z, Ballou AF, Downie CG, Arehart CH, Correa A, de Vries PS, Du Z, Gignoux CR, Gordon-Larsen P, Guo X, Haessler J, Howard AG, Hu Y, Kassahun H, Kent ST, Lopez JAG, Monda KL, North KE, Peters U, Preuss MH, Rich SS, Rhodes SL, Yao J, Yarosh R, Tsai MY, Rotter JI, Kooperberg CL, Loos RJF, Ballantyne C, Avery CL, Graff M. Lee MP, et al. Among authors: haessler j. Open Heart. 2023 Aug;10(2):e002382. doi: 10.1136/openhrt-2023-002382. Open Heart. 2023. PMID: 37648373 Free PMC article.
A loss-of-function CCR2 variant is associated with lower cardiovascular risk.
Georgakis MK, Malik R, Bounkari OE, Hasbani NR, Li J, Huffman JE, Shakt G, Tack RWP, Kimball TN, Asare Y, Morrison AC, Tsao NL, Judy R, Mitchell BD, Xu H, Montasser ME, Do R, Kenny EE, Loos RJF, Terry JG, Carr JJ, Bis JC, Psaty BM, Longstreth WT, Young KA, Lutz SM, Cho MH, Broome J, Khan AT, Wang FF, Heard-Costa N, Seshadri S, Vasan RS, Palmer ND, Freedman BI, Bowden DW, Yanek LR, Kral BG, Becker LC, Peyser PA, Bielak LF, Ammous F, Carson AP, Hall ME, Raffield LM, Rich SS, Post WS, Tracy RP, Taylor KD, Guo X, Mahaney MC, Curran JE, Blangero J, Clarke SL, Haessler JW, Hu Y, Assimes TL, Kooperberg C, Bernhagen J, Anderson CD, Damrauer SM, Zand R, Rotter JI, de Vries PS, Dichgans M. Georgakis MK, et al. Among authors: haessler jw. medRxiv [Preprint]. 2024 May 6:2023.08.14.23294063. doi: 10.1101/2023.08.14.23294063. medRxiv. 2024. PMID: 37645892 Free PMC article. Preprint.
158 results