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High-content multimodal analysis supports the IL-7/IL-7 receptor axis as a relevant therapeutic target in primary Sjögren's syndrome.
Desvaux E, Hemon P, Soret P, Le Dantec C, Chatzis L, Cornec D, Devauchelle-Pensec V; PRECISESADS clinical consortium; Elouej S, Duguet F, Laigle L, Poirier N, Moingeon P, Bretin S, Pers JO. Desvaux E, et al. Among authors: hemon p. J Autoimmun. 2023 Dec 18:103147. doi: 10.1016/j.jaut.2023.103147. Online ahead of print. J Autoimmun. 2023. PMID: 38114349
Decreased expression of the glucocorticoid receptor-GILZ pathway in Kupffer cells promotes liver inflammation in obese mice.
Robert O, Boujedidi H, Bigorgne A, Ferrere G, Voican CS, Vettorazzi S, Tuckermann JP, Bouchet-Delbos L, Tran T, Hemon P, Puchois V, Dagher I, Douard R, Gaudin F, Gary-Gouy H, Capel F, Durand-Gasselin I, Prévot S, Rousset S, Naveau S, Godot V, Emilie D, Lombès M, Perlemuter G, Cassard AM. Robert O, et al. Among authors: hemon p. J Hepatol. 2016 Apr;64(4):916-24. doi: 10.1016/j.jhep.2015.11.023. Epub 2015 Nov 27. J Hepatol. 2016. PMID: 26639395
CD8+ tissue-resident memory T cells are expanded in primary Sjögren's disease and can be therapeutically targeted by CD103 blockade.
Mauro D, Lin X, Pontarini E, Wehr P, Guggino G, Tang Y, Deng C, Gandolfo S, Xiao F, Rui K, Huang E, Tian J, Raimondo S, Rischmueller M, Boroky J, Downie-Doyle S, Nel H, Baz-Morelli A, Hsu A, Maraskovsky E, Barr A, Hemon P, Chatzis L, Boschetti CE, Colella G, Alessandro R, Rizzo A, Pers JO, Bombardieri M, Thomas R, Lu L, Ciccia F. Mauro D, et al. Among authors: hemon p. Ann Rheum Dis. 2024 May 22:ard-2023-225069. doi: 10.1136/ard-2023-225069. Online ahead of print. Ann Rheum Dis. 2024. PMID: 38777379
51 results