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Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells.
Deen AJ, Adinolfi S, Härkönen J, Patinen T, Liu X, Laitinen T, Takabe P, Kainulainen K, Pasonen-Seppänen S, Gawriyski LM, Arasu UT, Selvarajan I, Mäkinen P, Laitinen H, Kansanen E, Kaikkonen MU, Poso A, Varjosalo M, Levonen AL. Deen AJ, et al. Among authors: makinen p. Redox Biol. 2024 Feb;69:103031. doi: 10.1016/j.redox.2024.103031. Epub 2024 Jan 4. Redox Biol. 2024. PMID: 38184997 Free PMC article.
The absence of macrophage Nrf2 promotes early atherogenesis.
Ruotsalainen AK, Inkala M, Partanen ME, Lappalainen JP, Kansanen E, Mäkinen PI, Heinonen SE, Laitinen HM, Heikkilä J, Vatanen T, Hörkkö S, Yamamoto M, Ylä-Herttuala S, Jauhiainen M, Levonen AL. Ruotsalainen AK, et al. Among authors: makinen pi. Cardiovasc Res. 2013 Apr 1;98(1):107-15. doi: 10.1093/cvr/cvt008. Epub 2013 Jan 22. Cardiovasc Res. 2013. PMID: 23341579
Differential Promoter Methylation of Macrophage Genes Is Associated With Impaired Vascular Growth in Ischemic Muscles of Hyperlipidemic and Type 2 Diabetic Mice: Genome-Wide Promoter Methylation Study.
Babu M, Durga Devi T, Mäkinen P, Kaikkonen M, Lesch HP, Junttila S, Laiho A, Ghimire B, Gyenesei A, Ylä-Herttuala S. Babu M, et al. Among authors: makinen p. Circ Res. 2015 Jul 17;117(3):289-99. doi: 10.1161/CIRCRESAHA.115.306424. Epub 2015 Jun 17. Circ Res. 2015. PMID: 26085133
Aggravated Postinfarct Heart Failure in Type 2 Diabetes Is Associated with Impaired Mitophagy and Exaggerated Inflammasome Activation.
Durga Devi T, Babu M, Mäkinen P, Kaikkonen MU, Heinaniemi M, Laakso H, Ylä-Herttuala E, Rieppo L, Liimatainen T, Naumenko N, Tavi P, Ylä-Herttuala S. Durga Devi T, et al. Among authors: makinen p. Am J Pathol. 2017 Dec;187(12):2659-2673. doi: 10.1016/j.ajpath.2017.08.023. Epub 2017 Sep 19. Am J Pathol. 2017. PMID: 28935571 Free article.
Temporal Dynamics of Gene Expression During Endothelial Cell Differentiation From Human iPS Cells: A Comparison Study of Signalling Factors and Small Molecules.
Belt H, Koponen JK, Kekarainen T, Puttonen KA, Mäkinen PI, Niskanen H, Oja J, Wirth G, Koistinaho J, Kaikkonen MU, Ylä-Herttuala S. Belt H, et al. Front Cardiovasc Med. 2018 Mar 14;5:16. doi: 10.3389/fcvm.2018.00016. eCollection 2018. Front Cardiovasc Med. 2018. PMID: 29594149 Free PMC article.
HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells.
Arasu UT, Deen AJ, Pasonen-Seppänen S, Heikkinen S, Lalowski M, Kärnä R, Härkönen K, Mäkinen P, Lázaro-Ibáñez E, Siljander PR, Oikari S, Levonen AL, Rilla K. Arasu UT, et al. Among authors: makinen p. Cell Mol Life Sci. 2020 Oct;77(20):4093-4115. doi: 10.1007/s00018-019-03399-5. Epub 2019 Dec 9. Cell Mol Life Sci. 2020. PMID: 31820036 Free PMC article.
Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia.
Laitinen P, Väänänen MA, Kolari IL, Mäkinen PI, Kaikkonen MU, Weinberg MS, Morris KV, Korhonen P, Malm T, Ylä-Herttuala S, Roberts TC, Turunen MP, Turunen TA. Laitinen P, et al. Among authors: makinen pi. PLoS One. 2022 Mar 31;17(3):e0265948. doi: 10.1371/journal.pone.0265948. eCollection 2022. PLoS One. 2022. PMID: 35358280 Free PMC article.
Alzheimer's disease-induced phagocytic microglia express a specific profile of coding and non-coding RNAs.
Scoyni F, Giudice L, Väänänen MA, Downes N, Korhonen P, Choo XY, Välimäki NN, Mäkinen P, Korvenlaita N, Rozemuller AJ, de Vries HE, Polo J, Turunen TA, Ylä-Herttuala S, Hansen TB, Grubman A, Kaikkonen MU, Malm T. Scoyni F, et al. Among authors: makinen p. Alzheimers Dement. 2024 Feb;20(2):954-974. doi: 10.1002/alz.13502. Epub 2023 Oct 12. Alzheimers Dement. 2024. PMID: 37828821 Free PMC article.
200 results