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SIGMA leverages protein structural information to predict the pathogenicity of missense variants.
Zhao H, Du H, Zhao S, Chen Z, Li Y, Xu K, Liu B, Cheng X, Wen W, Li G, Chen G, Zhao Z, Qiu G; Deciphering Disorders Involving Scoliosis & Comorbidities (DISCO) Study; Liu P, Zhang TJ, Wu Z, Wu N. Zhao H, et al. Among authors: xu k. Cell Rep Methods. 2024 Jan 22;4(1):100687. doi: 10.1016/j.crmeth.2023.100687. Epub 2024 Jan 10. Cell Rep Methods. 2024. PMID: 38211594 Free PMC article.
Core planar cell polarity genes VANGL1 and VANGL2 in predisposition to congenital vertebral malformations.
Feng X, Ye Y, Zhang J, Zhang Y, Zhao S, Mak JCW, Otomo N, Zhao Z, Niu Y, Yonezawa Y, Li G, Lin M, Li X, Cheung PWH, Xu K, Takeda K, Wang S, Xie J, Kotani T, Choi VNT, Song YQ, Yang Y, Luk KDK, Lee KS, Li Z, Li PS, Leung CYH, Lin X, Wang X, Qiu G; DISCO (Deciphering disorders Involving Scoliosis and COmorbidities) study group; Watanabe K; Japanese Early Onset Scoliosis Research Group; Wu Z, Posey JE, Ikegawa S, Lupski JR, Cheung JPY, Zhang TJ, Gao B, Wu N. Feng X, et al. Among authors: xu k. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2310283121. doi: 10.1073/pnas.2310283121. Epub 2024 Apr 26. Proc Natl Acad Sci U S A. 2024. PMID: 38669183
CmBr confers fruit bitterness under CPPU treatment in melon.
Wang M, Jiang N, Xu Y, Chen X, Wang C, Wang C, Wang S, Xu K, Chai S, Yu Q, Zhang Z, Zhang H. Wang M, et al. Among authors: xu k. Plant Biotechnol J. 2024 May 30. doi: 10.1111/pbi.14399. Online ahead of print. Plant Biotechnol J. 2024. PMID: 38816932
The porcine skin microbiome exhibits broad fungal antagonism.
De La Cruz KF, Townsend EC, Alex Cheong JZ, Salamzade R, Liu A, Sandstrom S, Davila E, Huang L, Xu KH, Wu SY, Meudt JJ, Shanmuganayagam D, Gibson ALF, Kalan LR. De La Cruz KF, et al. Among authors: xu kh. Fungal Genet Biol. 2024 May 28:103898. doi: 10.1016/j.fgb.2024.103898. Online ahead of print. Fungal Genet Biol. 2024. PMID: 38815692
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