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A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer.
Cencic R, Im YK, Naineni SK, Moustafa-Kamal M, Jovanovic P, Sabourin V, Annis MG, Robert F, Schmeing TM, Koromilas A, Paquet M, Teodoro JG, Huang S, Siegel PM, Topisirovic I, Ursini-Siegel J, Pelletier J. Cencic R, et al. Among authors: pelletier j. Proc Natl Acad Sci U S A. 2024 Jan 23;121(4):e2318093121. doi: 10.1073/pnas.2318093121. Epub 2024 Jan 17. Proc Natl Acad Sci U S A. 2024. PMID: 38232291 Free PMC article.
Perturbations of RNA helicases in cancer.
Robert F, Pelletier J. Robert F, et al. Among authors: pelletier j. Wiley Interdiscip Rev RNA. 2013 Jul-Aug;4(4):333-49. doi: 10.1002/wrna.1163. Epub 2013 May 8. Wiley Interdiscip Rev RNA. 2013. PMID: 23658027 Review.
A comparative study of small molecules targeting eIF4A.
Naineni SK, Itoua Maïga R, Cencic R, Putnam AA, Amador LA, Rodriguez AD, Jankowsky E, Pelletier J. Naineni SK, et al. Among authors: pelletier j. RNA. 2020 May;26(5):541-549. doi: 10.1261/rna.072884.119. Epub 2020 Feb 3. RNA. 2020. PMID: 32014999 Free PMC article.
Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol.
Cencic R, Carrier M, Galicia-Vázquez G, Bordeleau ME, Sukarieh R, Bourdeau A, Brem B, Teodoro JG, Greger H, Tremblay ML, Porco JA Jr, Pelletier J. Cencic R, et al. Among authors: pelletier j. PLoS One. 2009;4(4):e5223. doi: 10.1371/journal.pone.0005223. Epub 2009 Apr 29. PLoS One. 2009. PMID: 19401772 Free PMC article.
1,994 results