Flotte TR - Search Results

1

Delivery of Adeno-Associated Virus Vectors to the Central Nervous System for Correction of Single Gene Disorders.

Daci R, Flotte TR. Daci R, et al. Among authors: flotte tr. Int J Mol Sci. 2024 Jan 15;25(2):1050. doi: 10.3390/ijms25021050. Int J Mol Sci. 2024. PMID: 38256124 Free PMC article. Review.

2

Immunogenicity of Recombinant Adeno-Associated Virus (AAV) Vectors for Gene Transfer.

Arjomandnejad M, Dasgupta I, Flotte TR, Keeler AM. Arjomandnejad M, et al. Among authors: flotte tr. BioDrugs. 2023 May;37(3):311-329. doi: 10.1007/s40259-023-00585-7. Epub 2023 Mar 2. BioDrugs. 2023. PMID: 36862289 Free PMC article. Review.

3

AAV5 delivery of CRISPR/Cas9 mediates genome editing in the lungs of young rhesus monkeys.

Liang SQ, Navia A, Ramseier M, Zhou X, Martinez ML, Lee CC, Zhou C, Wu J, Xie J, Su Q, Wang D, Flotte TR, Anderson DG, Tarantal AF, Shalek A, Gao G, Xue W. Liang SQ, et al. Among authors: flotte tr. Hum Gene Ther. 2024 May 20. doi: 10.1089/hum.2024.035. Online ahead of print. Hum Gene Ther. 2024. PMID: 38767512

4

Approaches to Therapeutic Gene Editing in Alpha-1 Antitrypsin Deficiency.

Gruntman AM, Xue W, Flotte TR. Gruntman AM, et al. Among authors: flotte tr. Methods Mol Biol. 2024;2750:11-17. doi: 10.1007/978-1-0716-3605-3_2. Methods Mol Biol. 2024. PMID: 38108963

5

Biodistribution and safety of a single rAAV3B-AAT vector for silencing and replacement of alpha-1 antitrypsin in Cynomolgus macaques.

Blackwood M, Gruntman AM, Tang Q, Pires-Ferreira D, Reil D, Kondratov O, Marsic D, Zolotukhin S, Gernoux G, Keeler AM, Mueller C, Flotte TR. Blackwood M, et al. Among authors: flotte tr. Mol Ther Methods Clin Dev. 2024 Jan 30;32(1):101200. doi: 10.1016/j.omtm.2024.101200. eCollection 2024 Mar 14. Mol Ther Methods Clin Dev. 2024. PMID: 38445045 Free PMC article.

6

Intrathecal gene therapy for neurologic disease in humans.

Flotte TR. Flotte TR. Mol Ther. 2024 May 1;32(5):1185-1186. doi: 10.1016/j.ymthe.2024.04.013. Epub 2024 Apr 24. Mol Ther. 2024. PMID: 38663405 No abstract available.

7

Gene therapy for alpha-1 antitrypsin deficiency: an update.

Pires Ferreira D, Gruntman AM, Flotte TR. Pires Ferreira D, et al. Among authors: flotte tr. Expert Opin Biol Ther. 2023 Mar;23(3):283-291. doi: 10.1080/14712598.2023.2183771. Epub 2023 Mar 2. Expert Opin Biol Ther. 2023. PMID: 36825473 Review.

8

Analyzing clinical observations to better understand and manage immune responses to AAV gene therapies.

Chan YK, Flotte TR. Chan YK, et al. Among authors: flotte tr. Mol Ther. 2023 Apr 5;31(4):913-914. doi: 10.1016/j.ymthe.2023.02.020. Epub 2023 Mar 15. Mol Ther. 2023. PMID: 36924775 Free PMC article. No abstract available.

9

Alpha-1 Antitrypsin Deficiency.

Gruntman AM, Xue W, Flotte TR. Gruntman AM, et al. Among authors: flotte tr. Methods Mol Biol. 2024;2750:1-7. doi: 10.1007/978-1-0716-3605-3_1. Methods Mol Biol. 2024. PMID: 38108962

10

Kenneth I. Berns, MD, PhD [1938-2024].

Byrne BJ, Flotte TR, Herzog RW, Srivastava A. Byrne BJ, et al. Among authors: flotte tr. Hum Gene Ther. 2024 Mar;35(5-6):133-134. doi: 10.1089/hum.2024.29266.kib. Hum Gene Ther. 2024. PMID: 38497910 No abstract available.

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