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Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair.
Saul D, Doolittle ML, Rowsey JL, Froemming MN, Kosinsky RL, Vos SJ, Ruan M, LeBrasseur N, Chandra A, Pignolo R, Passos JF, Farr JN, Monroe DG, Khosla S. Saul D, et al. bioRxiv [Preprint]. 2024 Feb 7:2024.02.01.578420. doi: 10.1101/2024.02.01.578420. bioRxiv. 2024. Update in: J Clin Invest. 2024 May 16:e179834. doi: 10.1172/JCI179834. PMID: 38370844 Free PMC article. Updated. Preprint.
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton.
Doolittle ML, Saul D, Kaur J, Rowsey JL, Vos SJ, Pavelko KD, Farr JN, Monroe DG, Khosla S. Doolittle ML, et al. Among authors: saul d. bioRxiv [Preprint]. 2023 Jan 13:2023.01.12.523760. doi: 10.1101/2023.01.12.523760. bioRxiv. 2023. Update in: Nat Commun. 2023 Jul 31;14(1):4587. doi: 10.1038/s41467-023-40393-9. PMID: 36711531 Free PMC article. Updated. Preprint.
In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers.
Samakkarnthai P, Saul D, Zhang L, Aversa Z, Doolittle ML, Sfeir JG, Kaur J, Atkinson EJ, Edwards JR, Russell RGG, Pignolo RJ, Kirkland JL, Tchkonia T, Niedernhofer LJ, Monroe DG, LeBrasseur NK, Farr JN, Robbins PD, Khosla S. Samakkarnthai P, et al. Among authors: saul d. bioRxiv [Preprint]. 2023 Feb 24:2023.02.23.529777. doi: 10.1101/2023.02.23.529777. bioRxiv. 2023. Update in: Aging (Albany NY). 2023 May 7;15(9):3331-3355. doi: 10.18632/aging.204701. PMID: 36865244 Free PMC article. Updated. Preprint.
Distinct secretomes in p16- and p21- positive senescent cells across tissues.
Saul D, Jurk D, Doolittle ML, Kosinsky RL, Monroe DG, LeBrasseur NK, Robbins PD, Niedernhofer LJ, Khosla S, Passos JF. Saul D, et al. bioRxiv [Preprint]. 2023 Dec 5:2023.12.05.569858. doi: 10.1101/2023.12.05.569858. bioRxiv. 2023. PMID: 38106149 Free PMC article. Preprint.
221 results