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Optimization Efforts for Identification of Novel Highly Potent Keap1-Nrf2 Protein-Protein Interaction Inhibitors.
J Med Chem. 2024 Mar 14;67(5):3741-3763. doi: 10.1021/acs.jmedchem.3c02171. Epub 2024 Feb 26.
J Med Chem. 2024.
PMID: 38408347
Methyl and Fluorine Effects in Novel Orally Bioavailable Keap1-Nrf2 PPI Inhibitor.
Otake K, Ubukata M, Nagahashi N, Ogawa N, Hantani Y, Hantani R, Adachi T, Nomura A, Yamaguchi K, Maekawa M, Mamada H, Motomura T, Sato M, Harada K.
Otake K, et al. Among authors: nagahashi n.
ACS Med Chem Lett. 2023 Apr 7;14(5):658-665. doi: 10.1021/acsmedchemlett.3c00067. eCollection 2023 May 11.
ACS Med Chem Lett. 2023.
PMID: 37197451
Free PMC article.
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Discovery of a Highly Potent and Selective MEK Inhibitor: GSK1120212 (JTP-74057 DMSO Solvate).
Abe H, Kikuchi S, Hayakawa K, Iida T, Nagahashi N, Maeda K, Sakamoto J, Matsumoto N, Miura T, Matsumura K, Seki N, Inaba T, Kawasaki H, Yamaguchi T, Kakefuda R, Nanayama T, Kurachi H, Hori Y, Yoshida T, Kakegawa J, Watanabe Y, Gilmartin AG, Richter MC, Moss KG, Laquerre SG.
Abe H, et al. Among authors: nagahashi n.
ACS Med Chem Lett. 2011 Feb 28;2(4):320-4. doi: 10.1021/ml200004g. eCollection 2011 Apr 14.
ACS Med Chem Lett. 2011.
PMID: 24900312
Free PMC article.
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C(2)-Symmetric bis-sulfoxide: A novel chiral auxiliary for asymmetric desymmetrization of cyclic meso-1,2-diols.
Maezaki N, Sakamoto A, Nagahashi N, Soejima M, Li YX, Imamura T, Kojima N, Ohishi H, Sakaguchi Ki, Iwata C, Tanaka T.
Maezaki N, et al. Among authors: nagahashi n.
J Org Chem. 2000 Jun 2;65(11):3284-91. doi: 10.1021/jo9919409.
J Org Chem. 2000.
PMID: 10843607
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Physicochemical parameters affecting the adhesion of ciprofloxacin-resistant Escherichia coli to activated sludge.
Nakaya Y, Nagahashi N, Hirano R, Ishizuka Y, Satoh H.
Nakaya Y, et al. Among authors: nagahashi n.
Water Sci Technol. 2024 May;89(9):2457-2467. doi: 10.2166/wst.2024.134. Epub 2024 Apr 26.
Water Sci Technol. 2024.
PMID: 38747960
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