Hoffmann S - Search Results

1

VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates.

Mirsanaye AS, Hoffmann S, Weisser M, Mund A, Lopez Mendez B, Typas D, van den Boom J, Benedict B, Hendriks IA, Nielsen ML, Meyer H, Duxin JP, Montoya G, Mailand N. Mirsanaye AS, et al. Among authors: hoffmann s. Nat Commun. 2024 Mar 19;15(1):2459. doi: 10.1038/s41467-024-46760-4. Nat Commun. 2024. PMID: 38503733 Free PMC article.

2

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.

Thorslund T, Ripplinger A, Hoffmann S, Wild T, Uckelmann M, Villumsen B, Narita T, Sixma TK, Choudhary C, Bekker-Jensen S, Mailand N. Thorslund T, et al. Among authors: hoffmann s. Nature. 2015 Nov 19;527(7578):389-93. doi: 10.1038/nature15401. Epub 2015 Oct 21. Nature. 2015. PMID: 26503038

3

TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.

Hoffmann S, Smedegaard S, Nakamura K, Mortuza GB, Räschle M, Ibañez de Opakua A, Oka Y, Feng Y, Blanco FJ, Mann M, Montoya G, Groth A, Bekker-Jensen S, Mailand N. Hoffmann S, et al. J Cell Biol. 2016 Jan 4;212(1):63-75. doi: 10.1083/jcb.201506071. Epub 2015 Dec 28. J Cell Biol. 2016. PMID: 26711499 Free PMC article.

4

SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication.

Walter D, Hoffmann S, Komseli ES, Rappsilber J, Gorgoulis V, Sørensen CS. Walter D, et al. Among authors: hoffmann s. Nat Commun. 2016 Jan 28;7:10530. doi: 10.1038/ncomms10530. Nat Commun. 2016. PMID: 26818844 Free PMC article.

5

Activation of the ATR kinase by the RPA-binding protein ETAA1.

Haahr P, Hoffmann S, Tollenaere MA, Ho T, Toledo LI, Mann M, Bekker-Jensen S, Räschle M, Mailand N. Haahr P, et al. Among authors: hoffmann s. Nat Cell Biol. 2016 Nov;18(11):1196-1207. doi: 10.1038/ncb3422. Epub 2016 Oct 10. Nat Cell Biol. 2016. PMID: 27723717

6

RADX interacts with single-stranded DNA to promote replication fork stability.

Schubert L, Ho T, Hoffmann S, Haahr P, Guérillon C, Mailand N. Schubert L, et al. Among authors: hoffmann s. EMBO Rep. 2017 Nov;18(11):1991-2003. doi: 10.15252/embr.201744877. Epub 2017 Oct 11. EMBO Rep. 2017. PMID: 29021206 Free PMC article.

7

ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability.

Haahr P, Borgermann N, Guo X, Typas D, Achuthankutty D, Hoffmann S, Shearer R, Sixma TK, Mailand N. Haahr P, et al. Among authors: hoffmann s. Mol Cell. 2018 Apr 5;70(1):165-174.e6. doi: 10.1016/j.molcel.2018.02.024. Epub 2018 Mar 22. Mol Cell. 2018. PMID: 29576528 Free article.

8

TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication.

Sonneville R, Bhowmick R, Hoffmann S, Mailand N, Hickson ID, Labib K. Sonneville R, et al. Among authors: hoffmann s. Elife. 2019 Sep 23;8:e48686. doi: 10.7554/eLife.48686. Elife. 2019. PMID: 31545170 Free PMC article.

9

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability.

Achuthankutty D, Thakur RS, Haahr P, Hoffmann S, Drainas AP, Bizard AH, Weischenfeldt J, Hickson ID, Mailand N. Achuthankutty D, et al. Among authors: hoffmann s. J Cell Biol. 2019 Dec 2;218(12):3943-3953. doi: 10.1083/jcb.201905064. Epub 2019 Oct 15. J Cell Biol. 2019. PMID: 31615875 Free PMC article.

10

FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease.

Hoffmann S, Pentakota S, Mund A, Haahr P, Coscia F, Gallo M, Mann M, Taylor NM, Mailand N. Hoffmann S, et al. EMBO Rep. 2020 Oct 5;21(10):e50662. doi: 10.15252/embr.202050662. Epub 2020 Aug 9. EMBO Rep. 2020. PMID: 32776417 Free PMC article.

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