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Defective mitochondria remodelling in B cells leads to an aged immune response.
Iborra-Pernichi M, Ruiz García J, Velasco de la Esperanza M, Estrada BS, Bovolenta ER, Cifuentes C, Prieto Carro C, González Martínez T, García-Consuegra J, Rey-Stolle MF, Rupérez FJ, Guerra Rodriguez M, Argüello RJ, Cogliati S, Martín-Belmonte F, Martínez-Martín N. Iborra-Pernichi M, et al. Among authors: martinez martin n. Nat Commun. 2024 Mar 22;15(1):2569. doi: 10.1038/s41467-024-46763-1. Nat Commun. 2024. PMID: 38519473 Free PMC article.
R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes.
Mendoza P, Martínez-Martín N, Bovolenta ER, Reyes-Garau D, Hernansanz-Agustín P, Delgado P, Diaz-Muñoz MD, Oeste CL, Fernández-Pisonero I, Castellano E, Martínez-Ruiz A, Alonso-Lopez D, Santos E, Bustelo XR, Kurosaki T, Alarcón B. Mendoza P, et al. Sci Signal. 2018 May 29;11(532):eaal1506. doi: 10.1126/scisignal.aal1506. Sci Signal. 2018. PMID: 29844052
Antigen phagocytosis by B cells is required for a potent humoral response.
Martínez-Riaño A, Bovolenta ER, Mendoza P, Oeste CL, Martín-Bermejo MJ, Bovolenta P, Turner M, Martínez-Martín N, Alarcón B. Martínez-Riaño A, et al. EMBO Rep. 2018 Sep;19(9):e46016. doi: 10.15252/embr.201846016. Epub 2018 Jul 9. EMBO Rep. 2018. PMID: 29987136 Free PMC article.
A call for accessible tools to unlock single-cell immunometabolism research.
Cosgrove J, Marçais A, Hartmann FJ, Bergthaler A, Zanoni I, Corrado M, Perié L, Cabezas-Wallscheid N, Bousso P, Alexandrov T, Kielian T, Martínez-Martín N, Opitz CA, Lyssiotis CA, Argüello RJ, Van den Bossche J. Cosgrove J, et al. Among authors: martinez martin n. Nat Metab. 2024 Apr 11. doi: 10.1038/s42255-024-01031-w. Online ahead of print. Nat Metab. 2024. PMID: 38605184 No abstract available.
Oncogenic Rag GTPase signaling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR.
Ortega-Molina A, Deleyto-Seldas N, Carreras J, Sanz A, Lebrero-Fernández C, Menéndez C, Vandenberg A, Fernández-Ruiz B, Marín-Arraiza L, de la Calle Arregui C, Belén Plata-Gómez A, Caleiras E, de Martino A, Martínez-Martín N, Troulé K, Piñeiro-Yáñez E, Nakamura N, Araf S, Victora GD, Okosun J, Fitzgibbon J, Efeyan A. Ortega-Molina A, et al. Nat Metab. 2019 Aug;1(8):775-789. doi: 10.1038/s42255-019-0098-8. Epub 2019 Aug 19. Nat Metab. 2019. PMID: 31579886 Free PMC article.
A switch from canonical to noncanonical autophagy shapes B cell responses.
Martinez-Martin N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, Tsui C, Burbage M, Keppler SJ, Montaner B, Jefferies HB, Nair U, Zhao YG, Domart MC, Collinson L, Bruckbauer A, Tooze SA, Batista FD. Martinez-Martin N, et al. Science. 2017 Feb 10;355(6325):641-647. doi: 10.1126/science.aal3908. Science. 2017. PMID: 28183981 Free PMC article.
79 results