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A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism.
Ptacin JL, Ma L, Caffaro CE, Acuff NV, Germar K, Severy P, Qu Y, Vela JL, Cai X, San Jose KM, Aerni HR, Chen DB, Esche E, Ismaili TK, Herman R, Pavlova Y, Pena MJ, Nguyen J, Koriazova LK, Shawver LK, Joseph IB, Mooney J, Peakman M, Milla ME. Ptacin JL, et al. Among authors: peakman m. Commun Med (Lond). 2024 Mar 26;4(1):58. doi: 10.1038/s43856-024-00485-z. Commun Med (Lond). 2024. PMID: 38532017 Free PMC article.
The role of OX40L/OX40 axis signalling in atopic dermatitis.
Guttman-Yassky E, Croft M, Geng B, Rynkiewicz N, Lucchesi D, Peakman M, van Krinks C, Valdecantos W, Xing H, Weidinger S. Guttman-Yassky E, et al. Among authors: peakman m. Br J Dermatol. 2024 Jun 5:ljae230. doi: 10.1093/bjd/ljae230. Online ahead of print. Br J Dermatol. 2024. PMID: 38836560
A set of circulating microRNAs belonging to the 14q32 chromosome locus identifies two subgroups of individuals with recent-onset type 1 diabetes.
Sebastiani G, Grieco GE, Bruttini M, Auddino S, Mori A, Toniolli M, Fignani D, Licata G, Aiello E, Nigi L, Formichi C, Fernandez-Tajes J, Pugliese A, Evans-Molina C, Overbergh L, Tree T, Peakman M, Mathieu C, Dotta F; INNODIA investigators. Sebastiani G, et al. Among authors: peakman m. Cell Rep Med. 2024 May 30:101591. doi: 10.1016/j.xcrm.2024.101591. Online ahead of print. Cell Rep Med. 2024. PMID: 38838677 Free article.
The INNODIA Type 1 Diabetes Natural History Study: a European cohort of newly diagnosed children, adolescents and adults.
Marcovecchio ML, Hendriks AEJ, Delfin C, Battelino T, Danne T, Evans ML, Johannesen J, Kaur S, Knip M, Overbergh L, Pociot F, Todd JA, Van der Schueren B, Wicker LS, Peakman M, Mathieu C; INNODIA consortium. Marcovecchio ML, et al. Among authors: peakman m. Diabetologia. 2024 Jun;67(6):995-1008. doi: 10.1007/s00125-024-06124-5. Epub 2024 Mar 22. Diabetologia. 2024. PMID: 38517484 Free PMC article.
Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes.
Hendriks AEJ, Marcovecchio ML, Besser REJ, Bonifacio E, Casteels K, Elding Larsson H, Gemulla G, Lundgren M, Kordonouri O, Mallone R, Pociot F, Szypowska A, Toppari J, Berge TVD, Ziegler AG, Mathieu C, Achenbach P; INNODIA consortium, the Fr1da Study Group and the GPPAD Study Group. Hendriks AEJ, et al. Diabetes Metab Res Rev. 2024 Feb;40(2):e3777. doi: 10.1002/dmrr.3777. Diabetes Metab Res Rev. 2024. PMID: 38375753
Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory.
Moulder R, Välikangas T, Hirvonen MK, Suomi T, Brorsson CA, Lietzén N, Bruggraber SFA, Overbergh L, Dunger DB, Peakman M, Chmura PJ, Brunak S, Schulte AM, Mathieu C, Knip M, Elo LL, Lahesmaa R; INNODIA consortium. Moulder R, et al. Among authors: peakman m. Diabetologia. 2023 Nov;66(11):1983-1996. doi: 10.1007/s00125-023-05974-9. Epub 2023 Aug 4. Diabetologia. 2023. PMID: 37537394 Free PMC article.
Tryptophan metabolism promotes immune evasion in human pancreatic β cells.
Rachdi L, Zhou Z, Berthault C, Lourenço C, Fouque A, Domet T, Armanet M, You S, Peakman M, Mallone R, Scharfmann R. Rachdi L, et al. Among authors: peakman m. EBioMedicine. 2023 Sep;95:104740. doi: 10.1016/j.ebiom.2023.104740. Epub 2023 Aug 1. EBioMedicine. 2023. PMID: 37536063 Free PMC article.
Gene expression signature predicts rate of type 1 diabetes progression.
Suomi T, Starskaia I, Kalim UU, Rasool O, Jaakkola MK, Grönroos T, Välikangas T, Brorsson C, Mazzoni G, Bruggraber S, Overbergh L, Dunger D, Peakman M, Chmura P, Brunak S, Schulte AM, Mathieu C, Knip M, Lahesmaa R, Elo LL; INNODIA Consortium. Suomi T, et al. Among authors: peakman m. EBioMedicine. 2023 Jun;92:104625. doi: 10.1016/j.ebiom.2023.104625. Epub 2023 May 22. EBioMedicine. 2023. PMID: 37224769 Free PMC article.
Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage.
Sioofy-Khojine AB, Richardson SJ, Locke JM, Oikarinen S, Nurminen N, Laine AP, Downes K, Lempainen J, Todd JA, Veijola R, Ilonen J, Knip M, Morgan NG, Hyöty H, Peakman M, Eichmann M. Sioofy-Khojine AB, et al. Among authors: peakman m. Diabetologia. 2022 Oct;65(10):1701-1709. doi: 10.1007/s00125-022-05753-y. Epub 2022 Jul 22. Diabetologia. 2022. PMID: 35867130 Free PMC article.
290 results