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A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism.
Ptacin JL, Ma L, Caffaro CE, Acuff NV, Germar K, Severy P, Qu Y, Vela JL, Cai X, San Jose KM, Aerni HR, Chen DB, Esche E, Ismaili TK, Herman R, Pavlova Y, Pena MJ, Nguyen J, Koriazova LK, Shawver LK, Joseph IB, Mooney J, Peakman M, Milla ME. Ptacin JL, et al. Commun Med (Lond). 2024 Mar 26;4(1):58. doi: 10.1038/s43856-024-00485-z. Commun Med (Lond). 2024. PMID: 38532017 Free PMC article.
Bacterial scaffold directs pole-specific centromere segregation.
Ptacin JL, Gahlmann A, Bowman GR, Perez AM, von Diezmann L, Eckart MR, Moerner WE, Shapiro L. Ptacin JL, et al. Proc Natl Acad Sci U S A. 2014 May 13;111(19):E2046-55. doi: 10.1073/pnas.1405188111. Epub 2014 Apr 28. Proc Natl Acad Sci U S A. 2014. PMID: 24778223 Free PMC article.
A spindle-like apparatus guides bacterial chromosome segregation.
Ptacin JL, Lee SF, Garner EC, Toro E, Eckart M, Comolli LR, Moerner WE, Shapiro L. Ptacin JL, et al. Nat Cell Biol. 2010 Aug;12(8):791-8. doi: 10.1038/ncb2083. Epub 2010 Jul 25. Nat Cell Biol. 2010. PMID: 20657594 Free PMC article.
17 results