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Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells.
Monteil VM, Wright SC, Dyczynski M, Kellner MJ, Appelberg S, Platzer SW, Ibrahim A, Kwon H, Pittarokoilis I, Mirandola M, Michlits G, Devignot S, Elder E, Abdurahman S, Bereczky S, Bagci B, Youhanna S, Aastrup T, Lauschke VM, Salata C, Elaldi N, Weber F, Monserrat N, Hawman DW, Feldmann H, Horn M, Penninger JM, Mirazimi A. Monteil VM, et al. Among authors: wright sc. Nat Microbiol. 2024 Jun;9(6):1499-1512. doi: 10.1038/s41564-024-01672-3. Epub 2024 Mar 28. Nat Microbiol. 2024. PMID: 38548922 Free PMC article.
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics.
Wright SC, Motso A, Koutsilieri S, Beusch CM, Sabatier P, Berghella A, Blondel-Tepaz É, Mangenot K, Pittarokoilis I, Sismanoglou DC, Le Gouill C, Olsen JV, Zubarev RA, Lambert NA, Hauser AS, Bouvier M, Lauschke VM. Wright SC, et al. Nat Commun. 2023 Oct 9;14(1):6243. doi: 10.1038/s41467-023-41893-4. Nat Commun. 2023. PMID: 37813859 Free PMC article.
The novel adrenergic agonist ATR-127 targets skeletal muscle and brown adipose tissue to tackle diabesity and steatohepatitis.
Talamonti E, Davegardh J, Kalinovich A, van Beek SMM, Dehvari N, Halleskog C, Bokhari HM, Hutchinson DS, Ham S, Humphrys LJ, Dijon NC, Motso A, Sandstrom A, Zacharewicz E, Mutule I, Suna E, Spura J, Ditrychova K, Stoddart LA, Holliday ND, Wright SC, Lauschke VM, Nielsen S, Scheele C, Cheesman E, Hoeks J, Molenaar P, Summers RJ, Pelcman B, Yakala GK, Bengtsson T. Talamonti E, et al. Among authors: wright sc. Mol Metab. 2024 May 17:101931. doi: 10.1016/j.molmet.2024.101931. Online ahead of print. Mol Metab. 2024. PMID: 38796310 Free article.
Frizzleds as GPCRs - More Conventional Than We Thought!
Schulte G, Wright SC. Schulte G, et al. Among authors: wright sc. Trends Pharmacol Sci. 2018 Sep;39(9):828-842. doi: 10.1016/j.tips.2018.07.001. Epub 2018 Jul 23. Trends Pharmacol Sci. 2018. PMID: 30049420 Review.
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes.
Kizilkaya HS, Sørensen KV, Madsen JS, Lindquist P, Douros JD, Bork-Jensen J, Berghella A, Gerlach PA, Gasbjerg LS, Mokrosiński J, Mowery SA, Knerr PJ, Finan B, Campbell JE, D'Alessio DA, Perez-Tilve D, Faas F, Mathiasen S, Rungby J, Sørensen HT, Vaag A, Nielsen JS, Holm JC, Lauenborg J, Damm P, Pedersen O, Linneberg A, Hartmann B, Holst JJ, Hansen T, Wright SC, Lauschke VM, Grarup N, Hauser AS, Rosenkilde MM. Kizilkaya HS, et al. Among authors: wright sc. Nat Metab. 2024 Jun 13. doi: 10.1038/s42255-024-01061-4. Online ahead of print. Nat Metab. 2024. PMID: 38871982
173 results