Fakih HH - Search Results

1

Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo.

Sarli SL, Fakih HH, Kelly K, Devi G, Rembetsy-Brown JM, McEachern HR, Ferguson CM, Echeverria D, Lee J, Sousa J, Sleiman HF, Khvorova A, Watts JK. Sarli SL, et al. Among authors: fakih hh. Nucleic Acids Res. 2024 May 22;52(9):4799-4817. doi: 10.1093/nar/gkae260. Nucleic Acids Res. 2024. PMID: 38613388 Free PMC article.

2

Precision spherical nucleic acids for delivery of anticancer drugs.

Bousmail D, Amrein L, Fakhoury JJ, Fakih HH, Hsu JCC, Panasci L, Sleiman HF. Bousmail D, et al. Among authors: fakih hh. Chem Sci. 2017 Sep 1;8(9):6218-6229. doi: 10.1039/c7sc01619k. Epub 2017 Jul 5. Chem Sci. 2017. PMID: 28989655 Free PMC article.

3

Minimalist Design of a Stimuli-Responsive Spherical Nucleic Acid for Conditional Delivery of Oligonucleotide Therapeutics.

Fakih HH, Fakhoury JJ, Bousmail D, Sleiman HF. Fakih HH, et al. ACS Appl Mater Interfaces. 2019 Apr 17;11(15):13912-13920. doi: 10.1021/acsami.8b18790. Epub 2019 Feb 5. ACS Appl Mater Interfaces. 2019. PMID: 30720262

4

Design Strategy to Access siRNA-Encapsulating DNA "Nanosuitcases" That Can Conditionally Release Their Cargo.

Bujold KE, Fakih HH, Sleiman HF. Bujold KE, et al. Among authors: fakih hh. Methods Mol Biol. 2019;1974:69-81. doi: 10.1007/978-1-4939-9220-1_6. Methods Mol Biol. 2019. PMID: 31098996

5

Detailed cellular assessment of albumin-bound oligonucleotides: Increased stability and lower non-specific cell uptake.

Lacroix A, Fakih HH, Sleiman HF. Lacroix A, et al. Among authors: fakih hh. J Control Release. 2020 Aug 10;324:34-46. doi: 10.1016/j.jconrel.2020.04.020. Epub 2020 Apr 21. J Control Release. 2020. PMID: 32330572

6

Design and enhanced gene silencing activity of spherical 2'-fluoroarabinose nucleic acids (FANA-SNAs).

Fakih HH, Katolik A, Malek-Adamian E, Fakhoury JJ, Kaviani S, Damha MJ, Sleiman HF. Fakih HH, et al. Chem Sci. 2021 Jan 15;12(8):2993-3003. doi: 10.1039/d0sc06645a. Chem Sci. 2021. PMID: 34164068 Free PMC article.

7

Stabilization of Functional DNA Structures with Mild Photochemical Methods.

Brown TM, Fakih HH, Saliba D, Asohan J, Sleiman HF. Brown TM, et al. Among authors: fakih hh. J Am Chem Soc. 2023 Feb 1;145(4):2142-2151. doi: 10.1021/jacs.2c08808. Epub 2023 Jan 18. J Am Chem Soc. 2023. PMID: 36651186

8

Sequence-Controlled Spherical Nucleic Acids: Gene Silencing, Encapsulation, and Cellular Uptake.

Kaviani S, Fakih HH, Asohan J, Katolik A, Damha MJ, Sleiman HF. Kaviani S, et al. Among authors: fakih hh. Nucleic Acid Ther. 2023 Aug;33(4):265-276. doi: 10.1089/nat.2022.0062. Epub 2023 May 17. Nucleic Acid Ther. 2023. PMID: 37196168

9

Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.

Tang Q, Fakih HH, Zain Ui Abideen M, Hildebrand SR, Afshari K, Gross KY, Sousa J, Maebius AS, Bartholdy C, Søgaard PP, Jackerott M, Hariharan V, Summers A, Fan X, Okamura K, Monopoli KR, Cooper DA, Echeverria D, Bramato B, McHugh N, Furgal RC, Dresser K, Winter SJ, Biscans A, Chuprin J, Haddadi NS, Sherman S, Yıldız-Altay Ü, Rashighi M, Richmond JM, Bouix-Peter C, Blanchard C, Clauss A, Alterman JF, Khvorova A, Harris JE. Tang Q, et al. Among authors: fakih hh. Nat Commun. 2023 Nov 4;14(1):7099. doi: 10.1038/s41467-023-42714-4. Nat Commun. 2023. PMID: 37925520 Free PMC article.

10

Editorial: Nucleic Acids Research virtual issue dedicated to nucleic acid therapeutics, 2018-2023.

Belgrad J, Fakih HH, Johnson KC, Corey DR. Belgrad J, et al. Among authors: fakih hh. Nucleic Acids Res. 2024 Jan 25;52(2):511-512. doi: 10.1093/nar/gkad1148. Nucleic Acids Res. 2024. PMID: 38035373 Free PMC article. No abstract available.

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