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Discovery of CRN04894: A Novel Potent Selective MC2R Antagonist.
Kim SH, Han S, Zhao J, Wang S, Kusnetzow AK, Reinhart G, Fowler MA, Markison S, Johns M, Luo R, Struthers RS, Zhu Y, Betz SF. Kim SH, et al. Among authors: fowler ma. ACS Med Chem Lett. 2024 Mar 19;15(4):478-485. doi: 10.1021/acsmedchemlett.3c00514. eCollection 2024 Apr 11. ACS Med Chem Lett. 2024. PMID: 38628803
Discovery of 4-(3-aminopyrrolidinyl)-3-aryl-5-(benzimidazol-2-yl)-pyridines as potent and selective SST5 agonists for the treatment of congenital hyperinsulinism.
Zhao J, Wang S, Hee Kim S, Han S, Rico-Bautista E, Sturchler E, Nguyen J, Tan H, Staley C, Karin Kusnetzow A, Betz SF, Johns M, Goulet L, Luo R, Fowler M, Athanacio J, Markison S, Scott Struthers R, Zhu Y. Zhao J, et al. Bioorg Med Chem Lett. 2022 Sep 1;71:128807. doi: 10.1016/j.bmcl.2022.128807. Epub 2022 May 20. Bioorg Med Chem Lett. 2022. PMID: 35605837
11-Ketotigogenin cellobioside (pamaqueside): a potent cholesterol absorption inhibitor in the hamster.
McCarthy PA, DeNinno MP, Morehouse LA, Chandler CE, Bangerter FW, Wilson TC, Urban FJ, Walinsky SW, Cosgrove PG, Duplantier K, Etienne JB, Fowler MA, Lambert JF, O'Donnell JP, Pezzullo SL, Watson HA Jr, Wilkins RW, Zaccaro LM, Zawistoski MP. McCarthy PA, et al. Among authors: fowler ma. J Med Chem. 1996 May 10;39(10):1935-7. doi: 10.1021/jm960123n. J Med Chem. 1996. PMID: 8642548 No abstract available.
46 results