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Rare X-linked variants carry predominantly male risk in autism, Tourette syndrome, and ADHD.
Wang S, Wang B, Drury V, Drake S, Sun N, Alkhairo H, Arbelaez J, Duhn C; Tourette International Collaborative Genetics (TIC Genetics); Bal VH, Langley K, Martin J, Hoekstra PJ, Dietrich A, Xing J, Heiman GA, Tischfield JA, Fernandez TV, Owen MJ, O'Donovan MC, Thapar A, State MW, Willsey AJ. Wang S, et al. Nat Commun. 2023 Dec 6;14(1):8077. doi: 10.1038/s41467-023-43776-0. Nat Commun. 2023. PMID: 38057346 Free PMC article.
Bcl6, Irf2, and Notch2 promote nonclassical monocyte development.
O'Connor KW, Liu T, Kim S, Briseño CG, Georgopoulos K, Murphy TL, Murphy KM. O'Connor KW, et al. Among authors: murphy tl. Proc Natl Acad Sci U S A. 2023 Aug 29;120(35):e2220853120. doi: 10.1073/pnas.2220853120. Epub 2023 Aug 22. Proc Natl Acad Sci U S A. 2023. PMID: 37607223 Free PMC article.
IL-6 selectively suppresses cDC1 specification via C/EBPβ.
Kim S, Chen J, Jo S, Ou F, Ferris ST, Liu TT, Ohara RA, Anderson DA, Wu R, Chen MY, Gillanders WE, Gillanders WE, Murphy TL, Murphy KM. Kim S, et al. Among authors: murphy tl. J Exp Med. 2023 Oct 2;220(10):e20221757. doi: 10.1084/jem.20221757. Epub 2023 Jul 11. J Exp Med. 2023. PMID: 37432392 Free PMC article.
WDFY4 deficiency in NOD mice ameliorates autoimmune diabetes and insulitis.
Ferris ST, Liu T, Chen J, Ohara RA, Ou F, Wu R, Kim S, Murphy TL, Murphy KM. Ferris ST, et al. Among authors: murphy tl. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2219956120. doi: 10.1073/pnas.2219956120. Epub 2023 Mar 20. Proc Natl Acad Sci U S A. 2023. PMID: 36940342 Free PMC article.
Genome-wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome.
Tsetsos F, Topaloudi A, Jain P, Yang Z, Yu D, Kolovos P, Tumer Z, Rizzo R, Hartmann A, Depienne C, Worbe Y, Müller-Vahl KR, Cath DC, Boomsma DI, Wolanczyk T, Zekanowski C, Barta C, Nemoda Z, Tarnok Z, Padmanabhuni SS, Buxbaum JD, Grice D, Glennon J, Stefansson H, Hengerer B, Yannaki E, Stamatoyannopoulos JA, Benaroya-Milshtein N, Cardona F, Hedderly T, Heyman I, Huyser C, Mir P, Morer A, Mueller N, Munchau A, Plessen KJ, Porcelli C, Roessner V, Walitza S, Schrag A, Martino D; PGC TS Working Group; TSAICG; TSGeneSEE Initiative; EMTICS Collaborative Group; TS-EUROTRAIN Network; TIC Genetics Collaborative Group; Tischfield JA, Heiman GA, Willsey AJ, Dietrich A, Davis LK, Crowley JJ, Mathews CA, Scharf JM, Georgitsi M, Hoekstra PJ, Paschou P. Tsetsos F, et al. Biol Psychiatry. 2023 Feb 2:S0006-3223(23)00051-3. doi: 10.1016/j.biopsych.2023.01.023. Online ahead of print. Biol Psychiatry. 2023. PMID: 36738982
Mechanisms of CD40-dependent cDC1 licensing beyond costimulation.
Wu R, Ohara RA, Jo S, Liu TT, Ferris ST, Ou F, Kim S, Theisen DJ, Anderson DA 3rd, Wong BW, Gershon T, Schreiber RD, Murphy TL, Murphy KM. Wu R, et al. Among authors: murphy tl. Nat Immunol. 2022 Nov;23(11):1536-1550. doi: 10.1038/s41590-022-01324-w. Epub 2022 Oct 21. Nat Immunol. 2022. PMID: 36271147 Free PMC article.
157 results