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A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic actions: Preclinical and phase I study.
Kaneko N, Loughrey CM, Smith G, Matsuda R, Hasunuma T, Mark PB, Toda M, Shinozaki M, Otani N, Kayley S, Da Silva Costa A, Martin TP, Dobi S, Saxena P, Shimamoto K, Ishikawa T, Kambayashi R, Riddell A, Elliott EB, McCarroll CS, Sakai T, Mitsuhisa Y, Hirano S, Kitai T, Kusano K, Inoue Y, Nakamura M, Kikuchi M, Toyoda S, Taguchi I, Fujiwara T, Sugiyama A, Kumagai Y, Iwata K. Kaneko N, et al. Among authors: martin tp. Br J Pharmacol. 2024 May 21. doi: 10.1111/bph.16379. Online ahead of print. Br J Pharmacol. 2024. PMID: 38773354
Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction.
Martin TP, MacDonald EA, Bradley A, Watson H, Saxena P, Rog-Zielinska EA, Raheem A, Fisher S, Elbassioni AAM, Almuzaini O, Booth C, Campbell M, Riddell A, Herzyk P, Blyth K, Nixon C, Zentilin L, Berry C, Braun T, Giacca M, McBride MW, Nicklin SA, Cameron ER, Loughrey CM. Martin TP, et al. Cardiovasc Res. 2023 Dec 19;119(16):2663-2671. doi: 10.1093/cvr/cvad107. Cardiovasc Res. 2023. PMID: 37433039 Free PMC article.
RUNX1: an emerging therapeutic target for cardiovascular disease.
Riddell A, McBride M, Braun T, Nicklin SA, Cameron E, Loughrey CM, Martin TP. Riddell A, et al. Among authors: martin tp. Cardiovasc Res. 2020 Jul 1;116(8):1410-1423. doi: 10.1093/cvr/cvaa034. Cardiovasc Res. 2020. PMID: 32154891 Free PMC article. Review.
110 results