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Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. 4. 2-Substituted dipyridodiazepinones as potent inhibitors of both wild-type and cysteine-181 HIV-1 reverse transcriptase enzymes.
Proudfoot JR, Hargrave KD, Kapadia SR, Patel UR, Grozinger KG, McNeil DW, Cullen E, Cardozo M, Tong L, Kelly TA, et al. Proudfoot JR, et al. J Med Chem. 1995 Nov 24;38(24):4830-8. doi: 10.1021/jm00024a010. J Med Chem. 1995. PMID: 7490732
Ligands for the tyrosine kinase p56lck SH2 domain: discovery of potent dipeptide derivatives with monocharged, nonhydrolyzable phosphate replacements.
Beaulieu PL, Cameron DR, Ferland JM, Gauthier J, Ghiro E, Gillard J, Gorys V, Poirier M, Rancourt J, Wernic D, Llinas-Brunet M, Betageri R, Cardozo M, Hickey ER, Ingraham R, Jakes S, Kabcenell A, Kirrane T, Lukas S, Patel U, Proudfoot J, Sharma R, Tong L, Moss N. Beaulieu PL, et al. J Med Chem. 1999 May 20;42(10):1757-66. doi: 10.1021/jm980676t. J Med Chem. 1999. PMID: 10346928
Nonpeptidic, monocharged, cell permeable ligands for the p56lck SH2 domain.
Proudfoot JR, Betageri R, Cardozo M, Gilmore TA, Glynn S, Hickey ER, Jakes S, Kabcenell A, Kirrane TM, Tibolla AK, Lukas S, Patel UR, Sharma R, Yazdanian M, Moss N, Beaulieu PL, Cameron DR, Ferland JM, Gauthier J, Gillard J, Gorys V, Poirier M, Rancourt J, Wernic D, Llinas-Brunet M. Proudfoot JR, et al. J Med Chem. 2001 Jul 19;44(15):2421-31. doi: 10.1021/jm000446q. J Med Chem. 2001. PMID: 11448224
Identification of dissociated non-steroidal glucocorticoid receptor agonists.
Kuzmich D, Kirrane T, Proudfoot J, Bekkali Y, Zindell R, Beck L, Nelson R, Shih CK, Kukulka AJ, Paw Z, Reilly P, Deleon R, Cardozo M, Nabozny G, Thomson D. Kuzmich D, et al. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5025-31. doi: 10.1016/j.bmcl.2007.07.031. Epub 2007 Jul 25. Bioorg Med Chem Lett. 2007. PMID: 17692519
35 results