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The glutathione cycle shapes synaptic glutamate activity.
Sedlak TW, Paul BD, Parker GM, Hester LD, Snowman AM, Taniguchi Y, Kamiya A, Snyder SH, Sawa A. Sedlak TW, et al. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2701-2706. doi: 10.1073/pnas.1817885116. Epub 2019 Jan 28. Proc Natl Acad Sci U S A. 2019. PMID: 30692251 Free PMC article.
Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation.
Giovinazzo D, Bursac B, Sbodio JI, Nalluru S, Vignane T, Snowman AM, Albacarys LM, Sedlak TW, Torregrossa R, Whiteman M, Filipovic MR, Snyder SH, Paul BD. Giovinazzo D, et al. Among authors: sedlak tw. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2017225118. doi: 10.1073/pnas.2017225118. Proc Natl Acad Sci U S A. 2021. PMID: 33431651 Free PMC article.
Glutathione is a physiologic reservoir of neuronal glutamate.
Koga M, Serritella AV, Messmer MM, Hayashi-Takagi A, Hester LD, Snyder SH, Sawa A, Sedlak TW. Koga M, et al. Among authors: sedlak tw. Biochem Biophys Res Commun. 2011 Jun 17;409(4):596-602. doi: 10.1016/j.bbrc.2011.04.087. Epub 2011 Apr 24. Biochem Biophys Res Commun. 2011. PMID: 21539809 Free PMC article.
Oxidative stress and inflammation in schizophrenia.
Sawa A, Sedlak TW. Sawa A, et al. Among authors: sedlak tw. Schizophr Res. 2016 Sep;176(1):1-2. doi: 10.1016/j.schres.2016.06.014. Epub 2016 Jul 6. Schizophr Res. 2016. PMID: 27395767 No abstract available.
Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide.
Vasavda C, Kothari R, Malla AP, Tokhunts R, Lin A, Ji M, Ricco C, Xu R, Saavedra HG, Sbodio JI, Snowman AM, Albacarys L, Hester L, Sedlak TW, Paul BD, Snyder SH. Vasavda C, et al. Among authors: sedlak tw. Cell Chem Biol. 2019 Oct 17;26(10):1450-1460.e7. doi: 10.1016/j.chembiol.2019.07.006. Epub 2019 Jul 25. Cell Chem Biol. 2019. PMID: 31353321 Free PMC article.
40 results