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A peptide nucleic acid-aminosugar conjugate targeting transactivation response element of HIV-1 RNA genome shows a high bioavailability in human cells and strongly inhibits tat-mediated transactivation of HIV-1 transcription.
Das I, Désiré J, Manvar D, Baussanne I, Pandey VN, Décout JL. Das I, et al. Among authors: desire j. J Med Chem. 2012 Jul 12;55(13):6021-32. doi: 10.1021/jm300253q. Epub 2012 Jun 22. J Med Chem. 2012. PMID: 22698070 Free PMC article.
Novel imino sugar α-glucosidase inhibitors as antiviral compounds.
Howe JD, Smith N, Lee MJ, Ardes-Guisot N, Vauzeilles B, Désiré J, Baron A, Blériot Y, Sollogoub M, Alonzi DS, Butters TD. Howe JD, et al. Among authors: desire j. Bioorg Med Chem. 2013 Aug 15;21(16):4831-8. doi: 10.1016/j.bmc.2013.03.014. Epub 2013 Mar 22. Bioorg Med Chem. 2013. PMID: 23582447
Neamine dimers targeting the HIV-1 TAR RNA.
Riguet E, Désiré J, Boden O, Ludwig V, Göbel M, Bailly C, Décout JL. Riguet E, et al. Among authors: desire j. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4651-5. doi: 10.1016/j.bmcl.2005.07.082. Bioorg Med Chem Lett. 2005. PMID: 16153833
42 results