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Use of isotopically chiral [4'-13C]penciclovir and 13C NMR to determine the specificity and absolute configuration of penciclovir phosphate esters formed in HSV-1 and HSV-2 infected cells and by HSV-1-encoded thymidine kinase.
Chirality. 1993;5(8):583-8. doi: 10.1002/chir.530050804.
Chirality. 1993.
PMID: 8305285
Mode of antiviral action of penciclovir in MRC-5 cells infected with herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus.
Earnshaw DL, Bacon TH, Darlison SJ, Edmonds K, Perkins RM, Vere Hodge RA.
Earnshaw DL, et al. Among authors: darlison sj.
Antimicrob Agents Chemother. 1992 Dec;36(12):2747-57. doi: 10.1128/AAC.36.12.2747.
Antimicrob Agents Chemother. 1992.
PMID: 1336346
Free PMC article.
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Use of isotopically chiral [4'-13C]famciclovir and 13C NMR to identify the chiral monoacetylated intermediates in the conversion of famciclovir to penciclovir by human intestinal wall extract.
Vere Hodge RA, Darlison SJ, Readshaw SA.
Vere Hodge RA, et al. Among authors: darlison sj.
Chirality. 1993;5(8):577-82. doi: 10.1002/chir.530050803.
Chirality. 1993.
PMID: 8305284
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