Watanabe KA - Search Results

1

CNAD: a potent and specific inhibitor of alcohol dehydrogenase.

Goldstein BM, Li H, Jones JP, Bell JE, Zeidler J, Pankiewicz KW, Watanabe KA. Goldstein BM, et al. Among authors: watanabe ka. J Med Chem. 1994 Feb 4;37(3):392-9. doi: 10.1021/jm00029a011. J Med Chem. 1994. PMID: 8308865

2

Crystallographic studies of isosteric NAD analogues bound to alcohol dehydrogenase: specificity and substrate binding in two ternary complexes.

Li H, Hallows WH, Punzi JS, Pankiewicz KW, Watanabe KA, Goldstein BM. Li H, et al. Among authors: watanabe ka. Biochemistry. 1994 Oct 4;33(39):11734-44. doi: 10.1021/bi00205a009. Biochemistry. 1994. PMID: 7918390

3

Synthesis of isosteric analogues of nicotinamide adenine dinucleotide containing C-nucleotide of nicotinamide or picolinamide.

Pankiewicz KW, Zeidler J, Ciszewski LA, Bell JE, Goldstein BM, Jayaram HN, Watanabe KA. Pankiewicz KW, et al. Among authors: watanabe ka. J Med Chem. 1993 Jun 25;36(13):1855-9. doi: 10.1021/jm00065a008. J Med Chem. 1993. PMID: 8099976

4

Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin.

Li H, Hallows WH, Punzi JS, Marquez VE, Carrell HL, Pankiewicz KW, Watanabe KA, Goldstein BM. Li H, et al. Among authors: watanabe ka. Biochemistry. 1994 Jan 11;33(1):23-32. doi: 10.1021/bi00167a004. Biochemistry. 1994. PMID: 8286346

5

The practical synthesis of a methylenebisphosphonate analogue of benzamide adenine dinucleotide: inhibition of human inosine monophosphate dehydrogenase (type I and II).

Pankiewicz KW, Lesiak K, Zatorski A, Goldstein BM, Carr SF, Sochacki M, Majumdar A, Seidman M, Watanabe KA. Pankiewicz KW, et al. Among authors: watanabe ka. J Med Chem. 1997 Apr 11;40(8):1287-91. doi: 10.1021/jm960641y. J Med Chem. 1997. PMID: 9111303

6

Synthesis and anti-HIV-1 activity of 2'-"up"-fluoro analogues of active anti-AIDS nucleosides 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (DDC).

Watanabe KA, Harada K, Zeidler J, Matulic-Adamic J, Takahashi K, Ren WY, Cheng LC, Fox JJ, Chou TC, Zhu QY, et al. Watanabe KA, et al. J Med Chem. 1990 Aug;33(8):2145-50. doi: 10.1021/jm00170a016. J Med Chem. 1990. PMID: 1695683

7

Synthesis of 1-methyl-5-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranosyl)uracil and 1-methyl-5-(3-azido-2,3-dideoxy-2-fluoro-beta-D-arabinofuranosyl)uracil. The C-nucleoside isostere of 3'-azido-3'-deoxythymidine and its 2'-"up"-fluoro analogue.

Sochacka E, Nawrot B, Pankiewicz KW, Watanabe KA. Sochacka E, et al. Among authors: watanabe ka. J Med Chem. 1990 Jul;33(7):1995-9. doi: 10.1021/jm00169a030. J Med Chem. 1990. PMID: 2362280

8

Nucleosides. 146. 1-Methyl-5-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil, the C-nucleoside isostere of the potent antiviral agent 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)thymine (FMAU). Studies directed toward the synthesis of 2'-deoxy-2'-substituted arabino nucleosides. 6.

Pankiewicz KW, Nawrot B, Gadler H, Price RW, Watanabe KA. Pankiewicz KW, et al. Among authors: watanabe ka. J Med Chem. 1987 Dec;30(12):2314-6. doi: 10.1021/jm00395a023. J Med Chem. 1987. PMID: 2824777

9

Synthesis of 5-beta-D-ribofuranosylnicotinamide and its N-methyl derivative. The isosteric and isoelectronic analogues of nicotinamide nucleoside.

Kabat MM, Pankiewicz KW, Watanabe KA. Kabat MM, et al. Among authors: watanabe ka. J Med Chem. 1987 May;30(5):924-7. doi: 10.1021/jm00388a030. J Med Chem. 1987. PMID: 2952800

10

Chemical synthesis of benzamide adenine dinucleotide: inhibition of inosine monophosphate dehydrogenase (types I and II).

Zatorski A, Watanabe KA, Carr SF, Goldstein BM, Pankiewicz KW. Zatorski A, et al. Among authors: watanabe ka. J Med Chem. 1996 Jun 7;39(12):2422-6. doi: 10.1021/jm9601415. J Med Chem. 1996. PMID: 8691436

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