Zhang X - Search Results

1

Medetomidine analogs as alpha 2-adrenergic ligands. 2. Design, synthesis, and biological activity of conformationally restricted naphthalene derivatives of medetomidine.

Zhang X, Yao XT, Dalton JT, Shams G, Lei L, Patil PN, Feller DR, Hsu FL, George C, Miller DD. Zhang X, et al. J Med Chem. 1996 Jul 19;39(15):3001-13. doi: 10.1021/jm9506074. J Med Chem. 1996. PMID: 8709134

2

Medetomidine analogs as alpha 2-adrenergic ligands. 3. Synthesis and biological evaluation of a new series of medetomidine analogs and their potential binding interactions with alpha 2-adrenoceptors involving a "methyl pocket".

Zhang X, De Los Angeles JE, He MY, Dalton JT, Shams G, Lei L, Patil PN, Feller DR, Miller DD, Hsu FL. Zhang X, et al. J Med Chem. 1997 Sep 12;40(19):3014-24. doi: 10.1021/jm960642q. J Med Chem. 1997. PMID: 9301663

3

Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists.

Katsura Y, Zhang X, Homma K, Rice KC, Calderon SN, Rothman RB, Yamamura HI, Davis P, Flippen-Anderson JL, Xu H, Becketts K, Foltz EJ, Porreca F. Katsura Y, et al. Among authors: zhang x. J Med Chem. 1997 Aug 29;40(18):2936-47. doi: 10.1021/jm970106d. J Med Chem. 1997. PMID: 9288176

4

Probes for narcotic receptor mediated phenomena. 26. Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic delta opioid receptor ligands.

Zhang X, Rice KC, Calderon SN, Kayakiri H, Smith L, Coop A, Jacobson AE, Rothman RB, Davis P, Dersch CM, Porreca F. Zhang X, et al. J Med Chem. 1999 Dec 30;42(26):5455-63. doi: 10.1021/jm9903895. J Med Chem. 1999. PMID: 10639287

5

Probes for narcotic receptor-mediated phenomena. 27. Synthesis and pharmacological evaluation of selective delta-opioid receptor agonists from 4-[(alphaR)-alpha-(2S,5R)-4-substituted-2, 5-dimethyl-1-piperazinyl-3-methoxybenzyl]-N,N-diethylbenzamides and their enantiomers.

Furness MS, Zhang X, Coop A, Jacobson AE, Rothman RB, Dersch CM, Xu H, Porreca F, Rice KC. Furness MS, et al. Among authors: zhang x. J Med Chem. 2000 Aug 10;43(16):3193-6. doi: 10.1021/jm0001222. J Med Chem. 2000. PMID: 10956228

6

Enantiomeric N-substituted N-normetazocines: a comparative study of affinities at sigma, PCP, and mu opioid receptors.

Carroll FI, Abraham P, Parham K, Bai X, Zhang X, Brine GA, Mascarella SW, Martin BR, May EL, Sauss C, et al. Carroll FI, et al. Among authors: zhang x. J Med Chem. 1992 Jul 24;35(15):2812-8. doi: 10.1021/jm00093a014. J Med Chem. 1992. PMID: 1322987

7

Synthesis and sigma binding properties of 2'-substituted 5,9 alpha-dimethyl-6,7-benzomorphans.

Danso-Danquah R, Bai X, Zhang X, Mascarella SW, Williams W, Sine B, Bowen WD, Carroll FI. Danso-Danquah R, et al. Among authors: zhang x. J Med Chem. 1995 Jul 21;38(15):2978-85. doi: 10.1021/jm00015a022. J Med Chem. 1995. PMID: 7636860

8

Synthesis and antibacterial activity of novel 6-O-substituted erythromycin A derivatives.

Clark RF, Ma Z, Wang S, Griesgraber G, Tufano M, Yong H, Li L, Zhang X, Nilius AM, Chu DT, Or YS. Clark RF, et al. Among authors: zhang x. Bioorg Med Chem Lett. 2000 Apr 17;10(8):815-9. doi: 10.1016/s0960-894x(00)00106-2. Bioorg Med Chem Lett. 2000. PMID: 10782693

9

Synthesis and sigma binding properties of 1'- and 3'-halo- and 1',3'-dihalo-N-normetazocine analogues.

Danso-Danquah R, Bai X, Zhang X, Mascarella SW, Williams W, Sine B, Bowen WD, Carroll FI. Danso-Danquah R, et al. Among authors: zhang x. J Med Chem. 1995 Jul 21;38(15):2986-9. doi: 10.1021/jm00015a023. J Med Chem. 1995. PMID: 7636861

10

Novel erythromycin derivatives with aryl groups tethered to the C-6 position are potent protein synthesis inhibitors and active against multidrug-resistant respiratory pathogens.

Ma Z, Clark RF, Brazzale A, Wang S, Rupp MJ, Li L, Griesgraber G, Zhang S, Yong H, Phan LT, Nemoto PA, Chu DT, Plattner JJ, Zhang X, Zhong P, Cao Z, Nilius AM, Shortridge VD, Flamm R, Mitten M, Meulbroek J, Ewing P, Alder J, Or YS. Ma Z, et al. Among authors: zhang s, zhang x. J Med Chem. 2001 Nov 22;44(24):4137-56. doi: 10.1021/jm0102349. J Med Chem. 2001. PMID: 11708916

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