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DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods.
Gilbert KM, Boos TL, Dersch CM, Greiner E, Jacobson AE, Lewis D, Matecka D, Prisinzano TE, Zhang Y, Rothman RB, Rice KC, Venanzi CA. Gilbert KM, et al. Among authors: matecka d. Bioorg Med Chem. 2007 Jan 15;15(2):1146-59. doi: 10.1016/j.bmc.2006.09.070. Epub 2006 Oct 1. Bioorg Med Chem. 2007. PMID: 17127069 Free PMC article.
Development of novel, potent, and selective dopamine reuptake inhibitors through alteration of the piperazine ring of 1-[2-(diphenylmethoxy)ethyl]-and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909).
Matecka D, Rothman RB, Radesca L, de Costa BR, Dersch CM, Partilla JS, Pert A, Glowa JR, Wojnicki FH, Rice KC. Matecka D, et al. J Med Chem. 1996 Nov 22;39(24):4704-16. doi: 10.1021/jm960305h. J Med Chem. 1996. PMID: 8941383
Studies of the biogenic amine transporters. VII. Characterization of a novel cocaine binding site identified with [125I]RTI-55 in membranes prepared from human, monkey and guinea pig caudate.
Rothman RB, Silverthorn ML, Glowa JR, Matecka D, Rice KC, Carroll FI, Partilla JS, Uhl GR, Vandenbergh DJ, Dersch CM. Rothman RB, et al. Among authors: matecka d. Synapse. 1998 Apr;28(4):322-38. doi: 10.1002/(SICI)1098-2396(199804)28:4<322::AID-SYN8>3.0.CO;2-B. Synapse. 1998. PMID: 9517841
17 results