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Scanning alanine mutagenesis and de-peptidization of a Candida albicans myristoyl-CoA:protein N-myristoyltransferase octapeptide substrate reveals three elements critical for molecular recognition.
McWherter CA, Rocque WJ, Zupec ME, Freeman SK, Brown DL, Devadas B, Getman DP, Sikorski JA, Gordon JI. McWherter CA, et al. Among authors: gordon ji. J Biol Chem. 1997 May 2;272(18):11874-80. doi: 10.1074/jbc.272.18.11874. J Biol Chem. 1997. PMID: 9115247 Free article.
N-myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA: protein N-myristoyltransferase.
Lodge JK, Jackson-Machelski E, Devadas B, Zupec ME, Getman DP, Kishore N, Freeman SK, McWherter CA, Sikorski JA, Gordon JI. Lodge JK, et al. Among authors: gordon ji. Microbiology (Reading). 1997 Feb;143 ( Pt 2):357-366. doi: 10.1099/00221287-143-2-357. Microbiology (Reading). 1997. PMID: 9043113 Free article.
Use of photoactivatable peptide substrates of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p) to characterize a myristoyl-CoA-Nmt1p-peptide ternary complex and to provide evidence for an ordered reaction mechanism.
Rudnick DA, Rocque WJ, McWherter CA, Toth MV, Jackson-Machelski E, Gordon JI. Rudnick DA, et al. Among authors: gordon ji. Proc Natl Acad Sci U S A. 1993 Feb 1;90(3):1087-91. doi: 10.1073/pnas.90.3.1087. Proc Natl Acad Sci U S A. 1993. PMID: 8430078 Free PMC article.
Conformationally constrained [p-(omega-aminoalkyl)phenacetyl]-L-seryl-L-lysyl dipeptide amides as potent peptidomimetic inhibitors of Candida albicans and human myristoyl-CoA:protein N-myristoyl transferase.
Nagarajan SR, Devadas B, Zupec ME, Freeman SK, Brown DL, Lu HF, Mehta PP, Kishore NS, McWherter CA, Getman DP, Gordon JI, Sikorski JA. Nagarajan SR, et al. Among authors: gordon ji. J Med Chem. 1997 May 9;40(10):1422-38. doi: 10.1021/jm9608671. J Med Chem. 1997. PMID: 9154965
528 results