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Sites of interaction between rod G-protein alpha-subunit and cGMP-phosphodiesterase gamma-subunit. Implications for the phosphodiesterase activation mechanism.
Artemyev NO, Rarick HM, Mills JS, Skiba NP, Hamm HE. Artemyev NO, et al. J Biol Chem. 1992 Dec 15;267(35):25067-72. J Biol Chem. 1992. PMID: 1334079 Free article.
The Kd for alpha tGTP gamma S.P gamma LY interaction was 36 nM. Addition of 1 microM alpha tGDP had no effect, but in the presence of A1F4-, alpha tGDP increased P gamma LY fluorescence by 85%. ...We demonstrate that an alpha t peptide, alpha t-293-314, which activated PDE …
The Kd for alpha tGTP gamma S.P gamma LY interaction was 36 nM. Addition of 1 microM alpha tGDP had no effect, but in the presence of …
An effector site that stimulates G-protein GTPase in photoreceptors.
Slepak VZ, Artemyev NO, Zhu Y, Dumke CL, Sabacan L, Sondek J, Hamm HE, Bownds MD, Arshavsky VY. Slepak VZ, et al. Among authors: artemyev no. J Biol Chem. 1995 Jun 16;270(24):14319-24. doi: 10.1074/jbc.270.24.14319. J Biol Chem. 1995. PMID: 7782290 Free article.
Subunit structure of rod cGMP-phosphodiesterase.
Artemyev NO, Surendran R, Lee JC, Hamm HE. Artemyev NO, et al. J Biol Chem. 1996 Oct 11;271(41):25382-8. doi: 10.1074/jbc.271.41.25382. J Biol Chem. 1996. PMID: 8810304 Free article.
115 results