Young IG - Search Results

1

The cytokine interleukin-5 (IL-5) effects cotransport of its receptor subunits to the nucleus in vitro.

Jans DA, Briggs LJ, Gustin SE, Jans P, Ford S, Young IG. Jans DA, et al. Among authors: young ig. FEBS Lett. 1997 Jun 30;410(2-3):368-72. doi: 10.1016/s0014-5793(97)00622-4. FEBS Lett. 1997. PMID: 9237664 Free article.

2

A functional bipartite nuclear localisation signal in the cytokine interleukin-5.

Jans DA, Briggs LJ, Gustin SE, Jans P, Ford S, Young IG. Jans DA, et al. Among authors: young ig. FEBS Lett. 1997 Apr 14;406(3):315-20. doi: 10.1016/s0014-5793(97)00293-7. FEBS Lett. 1997. PMID: 9136909 Free article.

3

Expression, crystallization and derivatization of the complete extracellular domain of the beta(c) subunit of the human IL-5, IL-3 and GM-CSF receptors.

Gustin SE, Church AP, Ford SC, Mann DA, Carr PD, Ollis DL, Young IG. Gustin SE, et al. Among authors: young ig. Eur J Biochem. 2001 May;268(10):2905-11. doi: 10.1046/j.1432-1327.2001.02178.x. Eur J Biochem. 2001. PMID: 11358507 Free article.

4

Interleukin-3 binding to the murine betaIL-3 and human betac receptors involves functional epitopes formed by domains 1 and 4 of different protein chains.

Murphy JM, Ford SC, Olsen JE, Gustin SE, Jeffrey PD, Ollis DL, Young IG. Murphy JM, et al. Among authors: young ig. J Biol Chem. 2004 Jun 18;279(25):26500-8. doi: 10.1074/jbc.M402705200. Epub 2004 Apr 1. J Biol Chem. 2004. PMID: 15060062 Free article.

5

Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration.

Carr PD, Gustin SE, Church AP, Murphy JM, Ford SC, Mann DA, Woltring DM, Walker I, Ollis DL, Young IG. Carr PD, et al. Among authors: young ig. Cell. 2001 Jan 26;104(2):291-300. doi: 10.1016/s0092-8674(01)00213-6. Cell. 2001. PMID: 11207369 Free article.

6

A novel functional epitope formed by domains 1 and 4 of the human common beta-subunit is involved in receptor activation by granulocyte macrophage colony-stimulating factor and interleukin 5.

Murphy JM, Ford SC, Wiedemann UM, Carr PD, Ollis DL, Young IG. Murphy JM, et al. Among authors: young ig. J Biol Chem. 2003 Mar 21;278(12):10572-7. doi: 10.1074/jbc.M211664200. Epub 2003 Jan 12. J Biol Chem. 2003. PMID: 12525483 Free article.

7

Clarification of the role of N-glycans on the common beta-subunit of the human IL-3, IL-5 and GM-CSF receptors and the murine IL-3 beta-receptor in ligand-binding and receptor activation.

Murphy JM, Soboleva TA, Mirza S, Ford SC, Olsen JE, Chen J, Young IG. Murphy JM, et al. Among authors: young ig. Cytokine. 2008 May;42(2):234-242. doi: 10.1016/j.cyto.2008.02.010. Epub 2008 Apr 18. Cytokine. 2008. PMID: 18374598

8

A new isoform of interleukin-3 receptor {alpha} with novel differentiation activity and high affinity binding mode.

Chen J, Olsen J, Ford S, Mirza S, Walker A, Murphy JM, Young IG. Chen J, et al. Among authors: young ig. J Biol Chem. 2009 Feb 27;284(9):5763-73. doi: 10.1074/jbc.M808197200. Epub 2008 Dec 24. J Biol Chem. 2009. PMID: 19109256 Free article.

9

An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope.

Carr PD, Conlan F, Ford S, Ollis DL, Young IG. Carr PD, et al. Among authors: young ig. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt 6):509-13. doi: 10.1107/S1744309106016812. Epub 2006 May 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16754968 Free PMC article.

10

Localization of the inducible enhancer in the mouse interleukin-5 gene that is responsive to T-cell receptor stimulation.

Bourke PF, van Leeuwen BH, Campbell HD, Young IG. Bourke PF, et al. Among authors: young ig. Blood. 1995 Apr 15;85(8):2069-77. Blood. 1995. PMID: 7718877 Free article.

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