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New orally active non-peptide fibrinogen receptor (GpIIb-IIIa) antagonists: identification of ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl) imino]methyl]phenyl]-1,3-thiazol-2-yl]-N-[1-[(ethoxycarbonyl)methyl]pip erid -4-yl]amino]propionate (SR 121787) as a potent and long-acting antithrombotic agent.
Badorc A, Bordes MF, de Cointet P, Savi P, Bernat A, Lalé A, Petitou M, Maffrand JP, Herbert JM. Badorc A, et al. Among authors: de cointet p. J Med Chem. 1997 Oct 10;40(21):3393-401. doi: 10.1021/jm970240y. J Med Chem. 1997. PMID: 9341914
SR 121787, a new orally active fibrinogen receptor antagonist.
Savi P, Badorc A, Lalé A, Bordes MF, Bornia J, Labouret C, Bernat A, de Cointet P, Hoffmann P, Maffrand JP, Herbert JM. Savi P, et al. Among authors: de cointet p. Thromb Haemost. 1998 Sep;80(3):469-76. Thromb Haemost. 1998. PMID: 9759629
SR 120819A, an orally-active and selective neuropeptide Y Y1 receptor antagonist.
Serradeil-Le Gal C, Valette G, Rouby PE, Pellet A, Oury-Donat F, Brossard G, Lespy L, Marty E, Neliat G, de Cointet P, et al. Serradeil-Le Gal C, et al. Among authors: de cointet p. FEBS Lett. 1995 Apr 3;362(2):192-6. doi: 10.1016/0014-5793(95)00230-7. FEBS Lett. 1995. PMID: 7720871 Free article.