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New orally active non-peptide fibrinogen receptor (GpIIb-IIIa) antagonists: identification of ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl) imino]methyl]phenyl]-1,3-thiazol-2-yl]-N-[1-[(ethoxycarbonyl)methyl]pip erid -4-yl]amino]propionate (SR 121787) as a potent and long-acting antithrombotic agent.
J Med Chem. 1997 Oct 10;40(21):3393-401. doi: 10.1021/jm970240y.
J Med Chem. 1997.
PMID: 9341914
SR 121787, a new orally active fibrinogen receptor antagonist.
Savi P, Badorc A, Lalé A, Bordes MF, Bornia J, Labouret C, Bernat A, de Cointet P, Hoffmann P, Maffrand JP, Herbert JM.
Savi P, et al. Among authors: de cointet p.
Thromb Haemost. 1998 Sep;80(3):469-76.
Thromb Haemost. 1998.
PMID: 9759629
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SR 120819A, an orally-active and selective neuropeptide Y Y1 receptor antagonist.
Serradeil-Le Gal C, Valette G, Rouby PE, Pellet A, Oury-Donat F, Brossard G, Lespy L, Marty E, Neliat G, de Cointet P, et al.
Serradeil-Le Gal C, et al. Among authors: de cointet p.
FEBS Lett. 1995 Apr 3;362(2):192-6. doi: 10.1016/0014-5793(95)00230-7.
FEBS Lett. 1995.
PMID: 7720871
Free article.
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1-Amino-substituted 4-methyl-5H-pyrido[4,3-b]indoles (gamma-carbolines) as tricyclic analogues of ellipticines: a new class of antineoplastic agents.
Bisagni E, Nguyen CH, Pierré A, Pépin O, de Cointet P, Gros P.
Bisagni E, et al. Among authors: de cointet p.
J Med Chem. 1988 Feb;31(2):398-405. doi: 10.1021/jm00397a023.
J Med Chem. 1988.
PMID: 3339609
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1-Amino-substituted 4-methyl-5H-pyrido[3',4':4,5]pyrrolo[3,2-c]pyridines: a new class of antineoplastic agents.
Nguyen CH, Bisagni E, Pepin O, Pierré A, de Cointet P.
Nguyen CH, et al. Among authors: de cointet p.
J Med Chem. 1987 Sep;30(9):1642-7. doi: 10.1021/jm00392a021.
J Med Chem. 1987.
PMID: 3625709
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Interrelationship between affinity for DNA, cytotoxicity and induction of DNA-breaks in cultured L1210 cells for two series of tricyclic intercalators. Simplified analogues of ellipticine derivatives.
Pierson V, Pierre A, de Cointet P, Nguyen CH, Bisagni E, Gros P.
Pierson V, et al. Among authors: de cointet p.
Biochem Pharmacol. 1989 May 1;38(9):1395-406. doi: 10.1016/0006-2952(89)90178-0.
Biochem Pharmacol. 1989.
PMID: 2719718
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