Street LJ - Search Results

1

3-[2-(Pyrrolidin-1-yl)ethyl]indoles and 3-[3-(piperidin-1-yl)propyl]indoles: agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B subtype.

Castro JL, Street LJ, Guiblin AR, Jelley RA, Russell MG, Sternfeld F, Beer MS, Stanton JA, Matassa VG. Castro JL, et al. Among authors: street lj. J Med Chem. 1997 Oct 24;40(22):3497-500. doi: 10.1021/jm9704558. J Med Chem. 1997. PMID: 9357514 No abstract available.

2

[3H]5-HT binding to cloned human, dog, and rat 5-HT1D and 5-HT1B receptors.

Stanton J, Castro L, MacLeod A, Sternfeld F, Street L, Beer M. Stanton J, et al. Ann N Y Acad Sci. 1998 Dec 15;861:266. doi: 10.1111/j.1749-6632.1998.tb10216.x. Ann N Y Acad Sci. 1998. PMID: 9928282 No abstract available.

3

Selective, orally active gamma-aminobutyric acidA alpha5 receptor inverse agonists as cognition enhancers.

Sternfeld F, Carling RW, Jelley RA, Ladduwahetty T, Merchant KJ, Moore KW, Reeve AJ, Street LJ, O'Connor D, Sohal B, Atack JR, Cook S, Seabrook G, Wafford K, Tattersall FD, Collinson N, Dawson GR, Castro JL, MacLeod AM. Sternfeld F, et al. Among authors: street lj. J Med Chem. 2004 Apr 22;47(9):2176-9. doi: 10.1021/jm031076j. J Med Chem. 2004. PMID: 15084116

4

Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha5 benzodiazepine binding site.

Street LJ, Sternfeld F, Jelley RA, Reeve AJ, Carling RW, Moore KW, McKernan RM, Sohal B, Cook S, Pike A, Dawson GR, Bromidge FA, Wafford KA, Seabrook GR, Thompson SA, Marshall G, Pillai GV, Castro JL, Atack JR, MacLeod AM. Street LJ, et al. J Med Chem. 2004 Jul 1;47(14):3642-57. doi: 10.1021/jm0407613. J Med Chem. 2004. PMID: 15214791

5

2,3,7-Trisubstituted pyrazolo[1,5-d][1,2,4]triazines: functionally selective GABAA alpha3-subtype agonists.

Carling RW, Russell MG, Moore KW, Mitchinson A, Guiblin A, Smith A, Wafford KA, Marshall G, Atack JR, Street LJ. Carling RW, et al. Among authors: street lj. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3550-4. doi: 10.1016/j.bmcl.2006.03.081. Epub 2006 Apr 18. Bioorg Med Chem Lett. 2006. PMID: 16621541

6

Synthesis and serotonergic activity of N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and analogues: potent agonists for 5-HT1D receptors.

Street LJ, Baker R, Davey WB, Guiblin AR, Jelley RA, Reeve AJ, Routledge H, Sternfeld F, Watt AP, Beer MS, et al. Street LJ, et al. J Med Chem. 1995 May 12;38(10):1799-810. doi: 10.1021/jm00010a025. J Med Chem. 1995. PMID: 7752204

7

L-694,247: a potent 5-HT1D receptor agonist.

Beer MS, Stanton JA, Bevan Y, Heald A, Reeve AJ, Street LJ, Matassa VG, Hargreaves RJ, Middlemiss DN. Beer MS, et al. Among authors: street lj. Br J Pharmacol. 1993 Nov;110(3):1196-200. doi: 10.1111/j.1476-5381.1993.tb13941.x. Br J Pharmacol. 1993. PMID: 8298808 Free PMC article.

8

Synthesis and serotonergic activity of 5-(oxadiazolyl)tryptamines: potent agonists for 5-HT1D receptors.

Street LJ, Baker R, Castro JL, Chambers MS, Guiblin AR, Hobbs SC, Matassa VG, Reeve AJ, Beer MS, Middlemiss DN, et al. Street LJ, et al. J Med Chem. 1993 May 28;36(11):1529-38. doi: 10.1021/jm00063a003. J Med Chem. 1993. PMID: 8496922

9

Selective, orally active 5-HT1D receptor agonists as potential antimigraine agents.

MacLeod AM, Street LJ, Reeve AJ, Jelley RA, Sternfeld F, Beer MS, Stanton JA, Watt AP, Rathbone D, Matassa VG. MacLeod AM, et al. Among authors: street lj. J Med Chem. 1997 Oct 24;40(22):3501-3. doi: 10.1021/jm9704560. J Med Chem. 1997. PMID: 9357515 No abstract available.

10

Synthesis and serotonergic activity of 3-[2-(pyrrolidin-1-yl)ethyl]indoles: potent agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B receptor.

Sternfeld F, Guiblin AR, Jelley RA, Matassa VG, Reeve AJ, Hunt PA, Beer MS, Heald A, Stanton JA, Sohal B, Watt AP, Street LJ. Sternfeld F, et al. Among authors: street lj. J Med Chem. 1999 Feb 25;42(4):677-90. doi: 10.1021/jm9805687. J Med Chem. 1999. PMID: 10052975

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