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T-1249 retains potent antiretroviral activity in patients who had experienced virological failure while on an enfuvirtide-containing treatment regimen.
Lalezari JP, Bellos NC, Sathasivam K, Richmond GJ, Cohen CJ, Myers RA Jr, Henry DH, Raskino C, Melby T, Murchison H, Zhang Y, Spence R, Greenberg ML, Demasi RA, Miralles GD; T1249-102 Study Group. Lalezari JP, et al. Among authors: demasi ra. J Infect Dis. 2005 Apr 1;191(7):1155-63. doi: 10.1086/427993. Epub 2005 Feb 22. J Infect Dis. 2005. PMID: 15747252 Clinical Trial.
Characterization of envelope glycoprotein gp41 genotype and phenotypic susceptibility to enfuvirtide at baseline and on treatment in the phase III clinical trials TORO-1 and TORO-2.
Melby T, Sista P, DeMasi R, Kirkland T, Roberts N, Salgo M, Heilek-Snyder G, Cammack N, Matthews TJ, Greenberg ML. Melby T, et al. Among authors: demasi r. AIDS Res Hum Retroviruses. 2006 May;22(5):375-85. doi: 10.1089/aid.2006.22.375. AIDS Res Hum Retroviruses. 2006. PMID: 16706613 Clinical Trial.
141 results