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Sequence analysis and homology modeling suggest that primary congenital glaucoma on 2p21 results from mutations disrupting either the hinge region or the conserved core structures of cytochrome P4501B1.
Am J Hum Genet. 1998 Mar;62(3):573-84. doi: 10.1086/301764.
Am J Hum Genet. 1998.
PMID: 9497261
Free PMC article.
A third locus (GLC1D) for adult-onset primary open-angle glaucoma maps to the 8q23 region.
Trifan OC, Traboulsi EI, Stoilova D, Alozie I, Nguyen R, Raja S, Sarfarazi M.
Trifan OC, et al. Among authors: alozie i.
Am J Ophthalmol. 1998 Jul;126(1):17-28. doi: 10.1016/s0002-9394(98)00073-7.
Am J Ophthalmol. 1998.
PMID: 9683145
Free article.
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Two craniosynostotic syndrome loci, Crouzon and Jackson-Weiss, map to chromosome 10q23-q26.
Li X, Lewanda AF, Eluma F, Jerald H, Choi H, Alozie I, Proukakis C, Talbot CC Jr, Vander Kolk C, Bird LM, et al.
Li X, et al. Among authors: alozie i.
Genomics. 1994 Jul 15;22(2):418-24. doi: 10.1006/geno.1994.1403.
Genomics. 1994.
PMID: 7806229
Free article.
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