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ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective analgesic acting via neuronal nicotinic acetylcholine receptors: I. In vitro characterization.
J Pharmacol Exp Ther. 1998 May;285(2):777-86.
J Pharmacol Exp Ther. 1998.
PMID: 9580626
Erysodine, a competitive antagonist at neuronal nicotinic acetylcholine receptors.
Decker MW, Anderson DJ, Brioni JD, Donnelly-Roberts DL, Kang CH, O'Neill AB, Piattoni-Kaplan M, Swanson S, Sullivan JP.
Decker MW, et al. Among authors: piattoni kaplan m.
Eur J Pharmacol. 1995 Jun 23;280(1):79-89. doi: 10.1016/0014-2999(95)00191-m.
Eur J Pharmacol. 1995.
PMID: 7498257
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(+/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors.
Sullivan JP, Decker MW, Brioni JD, Donnelly-Roberts D, Anderson DJ, Bannon AW, Kang CH, Adams P, Piattoni-Kaplan M, Buckley MJ, et al.
Sullivan JP, et al. Among authors: piattoni kaplan m.
J Pharmacol Exp Ther. 1994 Nov;271(2):624-31.
J Pharmacol Exp Ther. 1994.
PMID: 7965777
Item in Clipboard
Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor.
Gopalakrishnan M, Monteggia LM, Anderson DJ, Molinari EJ, Piattoni-Kaplan M, Donnelly-Roberts D, Arneric SP, Sullivan JP.
Gopalakrishnan M, et al. Among authors: piattoni kaplan m.
J Pharmacol Exp Ther. 1996 Jan;276(1):289-97.
J Pharmacol Exp Ther. 1996.
PMID: 8558445
Item in Clipboard
A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity alpha 4 beta 2 nicotinic acetylcholine receptor ligand.
Sullivan JP, Donnelly-Roberts D, Briggs CA, Anderson DJ, Gopalakrishnan M, Piattoni-Kaplan M, Campbell JE, McKenna DG, Molinari E, Hettinger AM, Garvey DS, Wasicak JT, Holladay MW, Williams M, Arneric SP.
Sullivan JP, et al. Among authors: piattoni kaplan m.
Neuropharmacology. 1996 Jun;35(6):725-34. doi: 10.1016/0028-3908(96)84644-2.
Neuropharmacology. 1996.
PMID: 8887981
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ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties.
Sullivan JP, Donnelly-Roberts D, Briggs CA, Anderson DJ, Gopalakrishnan M, Xue IC, Piattoni-Kaplan M, Molinari E, Campbell JE, McKenna DG, Gunn DE, Lin NH, Ryther KB, He Y, Holladay MW, Wonnacott S, Williams M, Arneric SP.
Sullivan JP, et al. Among authors: piattoni kaplan m.
J Pharmacol Exp Ther. 1997 Oct;283(1):235-46.
J Pharmacol Exp Ther. 1997.
PMID: 9336329
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Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors.
Holladay MW, Wasicak JT, Lin NH, He Y, Ryther KB, Bannon AW, Buckley MJ, Kim DJ, Decker MW, Anderson DJ, Campbell JE, Kuntzweiler TA, Donnelly-Roberts DL, Piattoni-Kaplan M, Briggs CA, Williams M, Arneric SP.
Holladay MW, et al. Among authors: piattoni kaplan m.
J Med Chem. 1998 Feb 12;41(4):407-12. doi: 10.1021/jm9706224.
J Med Chem. 1998.
PMID: 9484491
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Human alpha 7 nicotinic acetylcholine receptor responses to novel ligands.
Briggs CA, McKenna DG, Piattoni-Kaplan M.
Briggs CA, et al. Among authors: piattoni kaplan m.
Neuropharmacology. 1995 Jun;34(6):583-90. doi: 10.1016/0028-3908(95)00028-5.
Neuropharmacology. 1995.
PMID: 7566493
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