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Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase.
von Janta-Lipinski M, Costisella B, Ochs H, Hübscher U, Hafkemeyer P, Matthes E. von Janta-Lipinski M, et al. Among authors: costisella b. J Med Chem. 1998 Jun 4;41(12):2040-6. doi: 10.1021/jm9704210. J Med Chem. 1998. PMID: 9622545
Ras-mediated cleavage of a GTP analogue by a novel mechanism.
Gail R, Costisella B, Ahmadian MR, Wittinghofer A. Gail R, et al. Among authors: costisella b. Chembiochem. 2001 Aug 3;2(7-8):570-5. doi: 10.1002/1439-7633(20010803)2:7/8<570::AID-CBIC570>3.0.CO;2-L. Chembiochem. 2001. PMID: 11828490
PhzA/B catalyzes the formation of the tricycle in phenazine biosynthesis.
Ahuja EG, Janning P, Mentel M, Graebsch A, Breinbauer R, Hiller W, Costisella B, Thomashow LS, Mavrodi DV, Blankenfeldt W. Ahuja EG, et al. Among authors: costisella b. J Am Chem Soc. 2008 Dec 17;130(50):17053-61. doi: 10.1021/ja806325k. J Am Chem Soc. 2008. PMID: 19053436
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