Dahring TK - Search Results

1

Structure-activity relationships for 1-phenylbenzimidazoles as selective ATP site inhibitors of the platelet-derived growth factor receptor.

Palmer BD, Smaill JB, Boyd M, Boschelli DH, Doherty AM, Hamby JM, Khatana SS, Kramer JB, Kraker AJ, Panek RL, Lu GH, Dahring TK, Winters RT, Showalter HD, Denny WA. Palmer BD, et al. Among authors: dahring tk. J Med Chem. 1998 Dec 31;41(27):5457-65. doi: 10.1021/jm9804681. J Med Chem. 1998. PMID: 9876115

2

Structure-activity relationships for a novel series of pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors.

Hamby JM, Connolly CJ, Schroeder MC, Winters RT, Showalter HD, Panek RL, Major TC, Olsewski B, Ryan MJ, Dahring T, Lu GH, Keiser J, Amar A, Shen C, Kraker AJ, Slintak V, Nelson JM, Fry DW, Bradford L, Hallak H, Doherty AM. Hamby JM, et al. J Med Chem. 1997 Jul 18;40(15):2296-303. doi: 10.1021/jm970367n. J Med Chem. 1997. PMID: 9240345

3

2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity.

Klutchko SR, Hamby JM, Boschelli DH, Wu Z, Kraker AJ, Amar AM, Hartl BG, Shen C, Klohs WD, Steinkampf RW, Driscoll DL, Nelson JM, Elliott WL, Roberts BJ, Stoner CL, Vincent PW, Dykes DJ, Panek RL, Lu GH, Major TC, Dahring TK, Hallak H, Bradford LA, Showalter HD, Doherty AM. Klutchko SR, et al. Among authors: dahring tk. J Med Chem. 1998 Aug 13;41(17):3276-92. doi: 10.1021/jm9802259. J Med Chem. 1998. PMID: 9703473

4

Design of peptidomimetics that inhibit the association of phosphatidylinositol 3-kinase with platelet-derived growth factor-beta receptor and possess cellular activity.

Eaton SR, Cody WL, Doherty AM, Holland DR, Panek RL, Lu GH, Dahring TK, Rose DR. Eaton SR, et al. Among authors: dahring tk. J Med Chem. 1998 Oct 22;41(22):4329-42. doi: 10.1021/jm9802766. J Med Chem. 1998. PMID: 9784108

5

Synthesis and tyrosine kinase inhibitory activity of a series of 2-amino-8H-pyrido[2,3-d]pyrimidines: identification of potent, selective platelet-derived growth factor receptor tyrosine kinase inhibitors.

Boschelli DH, Wu Z, Klutchko SR, Showalter HD, Hamby JM, Lu GH, Major TC, Dahring TK, Batley B, Panek RL, Keiser J, Hartl BG, Kraker AJ, Klohs WD, Roberts BJ, Patmore S, Elliott WL, Steinkampf R, Bradford LA, Hallak H, Doherty AM. Boschelli DH, et al. Among authors: dahring tk. J Med Chem. 1998 Oct 22;41(22):4365-77. doi: 10.1021/jm980398y. J Med Chem. 1998. PMID: 9784112

6

Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity.

Schroeder MC, Hamby JM, Connolly CJ, Grohar PJ, Winters RT, Barvian MR, Moore CW, Boushelle SL, Crean SM, Kraker AJ, Driscoll DL, Vincent PW, Elliott WL, Lu GH, Batley BL, Dahring TK, Major TC, Panek RL, Doherty AM, Showalter HD. Schroeder MC, et al. Among authors: dahring tk. J Med Chem. 2001 Jun 7;44(12):1915-26. doi: 10.1021/jm0004291. J Med Chem. 2001. PMID: 11384237

7

Inhibition of growth factor-mediated tyrosine phosphorylation in vascular smooth muscle by PD 089828, a new synthetic protein tyrosine kinase inhibitor.

Dahring TK, Lu GH, Hamby JM, Batley BL, Kraker AJ, Panek RL. Dahring TK, et al. J Pharmacol Exp Ther. 1997 Jun;281(3):1446-56. J Pharmacol Exp Ther. 1997. PMID: 9190882

8

In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase.

Panek RL, Lu GH, Dahring TK, Batley BL, Connolly C, Hamby JM, Brown KJ. Panek RL, et al. Among authors: dahring tk. J Pharmacol Exp Ther. 1998 Jul;286(1):569-77. J Pharmacol Exp Ther. 1998. PMID: 9655904

9

In vitro pharmacological characterization of PD 166285, a new nanomolar potent and broadly active protein tyrosine kinase inhibitor.

Panek RL, Lu GH, Klutchko SR, Batley BL, Dahring TK, Hamby JM, Hallak H, Doherty AM, Keiser JA. Panek RL, et al. Among authors: dahring tk. J Pharmacol Exp Ther. 1997 Dec;283(3):1433-44. J Pharmacol Exp Ther. 1997. PMID: 9400019

10

Inhibition of FGF-1 receptor tyrosine kinase activity by PD 161570, a new protein-tyrosine kinase inhibitor.

Batley BL, Doherty AM, Hamby JM, Lu GH, Keller P, Dahring TK, Hwang O, Crickard K, Panek RL. Batley BL, et al. Among authors: dahring tk. Life Sci. 1998;62(2):143-50. doi: 10.1016/s0024-3205(97)01060-6. Life Sci. 1998. PMID: 9488112

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