EY018383/EY/NEI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2008	4
2010	3
2011	5
2012	4
2013	3
2014	3
2015	4
2016	2
2018	4
2019	2
2020	2
2021	3
2022	2
2023	4
2024	1

1

Cholesterol in the retina: the best is yet to come.

Pikuleva IA, Curcio CA. Pikuleva IA, et al. Prog Retin Eye Res. 2014 Jul;41:64-89. doi: 10.1016/j.preteyeres.2014.03.002. Epub 2014 Apr 4. Prog Retin Eye Res. 2014. PMID: 24704580 Free PMC article. Review.

2

Challenges and Opportunities in P450 Research on the Eye.

Pikuleva IA. Pikuleva IA. Drug Metab Dispos. 2023 Oct;51(10):1295-1307. doi: 10.1124/dmd.122.001072. Epub 2023 Mar 13. Drug Metab Dispos. 2023. PMID: 36914277 Free PMC article. Review.

3

2-Hydroxypropyl-β-cyclodextrin reduces retinal cholesterol in wild-type and Cyp27a1^-/- Cyp46a1^-/- mice with deficiency in the oxysterol production.

El-Darzi N, Mast N, Petrov AM, Pikuleva IA. El-Darzi N, et al. Br J Pharmacol. 2021 Aug;178(16):3220-3234. doi: 10.1111/bph.15209. Epub 2020 Aug 13. Br J Pharmacol. 2021. PMID: 32698250 Free PMC article.

4

The normalizing effects of the CYP46A1 activator efavirenz on retinal sterol levels and risk factors for glaucoma in Apoj^-/- mice.

El-Darzi N, Mast N, Li Y, Dailey B, Kang M, Rhee DJ, Pikuleva IA. El-Darzi N, et al. Cell Mol Life Sci. 2023 Jul 1;80(7):194. doi: 10.1007/s00018-023-04848-y. Cell Mol Life Sci. 2023. PMID: 37392222 Free PMC article.

5

Characterizations of Hamster Retina as a Model for Studies of Retinal Cholesterol Homeostasis.

El-Darzi N, Mast N, Dailey B, Denker J, Li Y, Vance J, Pikuleva IA. El-Darzi N, et al. Biology (Basel). 2021 Oct 6;10(10):1003. doi: 10.3390/biology10101003. Biology (Basel). 2021. PMID: 34681102 Free PMC article.

6

Studies of ApoD^-/- and ApoD^-/-ApoE^-/- mice uncover the APOD significance for retinal metabolism, function, and status of chorioretinal blood vessels.

El-Darzi N, Mast N, Petrov AM, Dao T, Astafev AA, Saadane A, Prendergast E, Schwarz E, Bederman I, Pikuleva IA. El-Darzi N, et al. Cell Mol Life Sci. 2021 Feb;78(3):963-983. doi: 10.1007/s00018-020-03546-3. Epub 2020 May 21. Cell Mol Life Sci. 2021. PMID: 32440710 Free PMC article.

7

Mechanisms that minimize retinal impact of apolipoprotein E absence.

Saadane A, Petrov A, Mast N, El-Darzi N, Dao T, Alnemri A, Song Y, Dunaief JL, Pikuleva IA. Saadane A, et al. J Lipid Res. 2018 Dec;59(12):2368-2382. doi: 10.1194/jlr.M090043. Epub 2018 Oct 17. J Lipid Res. 2018. PMID: 30333155 Free PMC article.

8

Retinal Hypercholesterolemia Triggers Cholesterol Accumulation and Esterification in Photoreceptor Cells.

Saadane A, Mast N, Dao T, Ahmad B, Pikuleva IA. Saadane A, et al. J Biol Chem. 2016 Sep 23;291(39):20427-39. doi: 10.1074/jbc.M116.744656. Epub 2016 Aug 11. J Biol Chem. 2016. PMID: 27514747 Free PMC article.

9

2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis.

El-Darzi N, Mast N, Hammer SS, Dorweiler TF, Busik JV, Pikuleva IA. El-Darzi N, et al. J Lipid Res. 2023 Feb;64(2):100323. doi: 10.1016/j.jlr.2022.100323. Epub 2022 Dec 29. J Lipid Res. 2023. PMID: 36586438 Free PMC article.

10

Cholesterol-metabolizing cytochromes P450: implications for cholesterol lowering.

Pikuleva IA. Pikuleva IA. Expert Opin Drug Metab Toxicol. 2008 Nov;4(11):1403-14. doi: 10.1517/17425255.4.11.1403. Expert Opin Drug Metab Toxicol. 2008. PMID: 18950282 Free PMC article. Review.

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