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Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity.
EMBO Rep. 2004 Jun;5(6):643-8. doi: 10.1038/sj.embor.7400153. Epub 2004 May 21.
EMBO Rep. 2004.
PMID: 15153933
Free PMC article.
Cytochrome c release from mitochondria proceeds by a two-step process.
Ott M, Robertson JD, Gogvadze V, Zhivotovsky B, Orrenius S.
Ott M, et al.
Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1259-63. doi: 10.1073/pnas.241655498. Epub 2002 Jan 29.
Proc Natl Acad Sci U S A. 2002.
PMID: 11818574
Free PMC article.
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