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2019 | 1 |
2021 | 1 |
2022 | 1 |
2024 | 0 |
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Ubiquitin-mediated DNA damage response is synthetic lethal with G-quadruplex stabilizer CX-5461.
Sci Rep. 2021 May 7;11(1):9812. doi: 10.1038/s41598-021-88988-w.
Sci Rep. 2021.
PMID: 33963218
Free PMC article.
Results of the phase I CCTG IND.231 trial of CX-5461 in patients with advanced solid tumors enriched for DNA-repair deficiencies.
Hilton J, Gelmon K, Bedard PL, Tu D, Xu H, Tinker AV, Goodwin R, Laurie SA, Jonker D, Hansen AR, Veitch ZW, Renouf DJ, Hagerman L, Lui H, Chen B, Kellar D, Li I, Lee SE, Kono T, Cheng BYC, Yap D, Lai D, Beatty S, Soong J, Pritchard KI, Soria-Bretones I, Chen E, Feilotter H, Rushton M, Seymour L, Aparicio S, Cescon DW.
Hilton J, et al.
Nat Commun. 2022 Jun 24;13(1):3607. doi: 10.1038/s41467-022-31199-2.
Nat Commun. 2022.
PMID: 35750695
Free PMC article.
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Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation.
Mazloomian A, Araki S, Ohori M, El-Naggar AM, Yap D, Bashashati A, Nakao S, Sorensen PH, Nakanishi A, Shah S, Aparicio S.
Mazloomian A, et al.
Commun Biol. 2019 May 3;2:165. doi: 10.1038/s42003-019-0391-9. eCollection 2019.
Commun Biol. 2019.
PMID: 31069274
Free PMC article.
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