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Chromosomally Integrated Human Herpesvirus 6: Models of Viral Genome Release from the Telomere and Impacts on Human Health.
Viruses. 2017 Jul 12;9(7):184. doi: 10.3390/v9070184.
Viruses. 2017.
PMID: 28704957
Free PMC article.
Review.
Variation in human herpesvirus 6B telomeric integration, excision, and transmission between tissues and individuals.
Wood ML, Veal CD, Neumann R, Suárez NM, Nichols J, Parker AJ, Martin D, Romaine SP, Codd V, Samani NJ, Voors AA, Tomaszewski M, Flamand L, Davison AJ, Royle NJ.
Wood ML, et al.
Elife. 2021 Sep 21;10:e70452. doi: 10.7554/eLife.70452.
Elife. 2021.
PMID: 34545807
Free PMC article.
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Inherited Chromosomally Integrated Human Herpesvirus 6 Genomes Are Ancient, Intact, and Potentially Able To Reactivate from Telomeres.
Zhang E, Bell AJ, Wilkie GS, Suárez NM, Batini C, Veal CD, Armendáriz-Castillo I, Neumann R, Cotton VE, Huang Y, Porteous DJ, Jarrett RF, Davison AJ, Royle NJ.
Zhang E, et al.
J Virol. 2017 Oct 27;91(22):e01137-17. doi: 10.1128/JVI.01137-17. Print 2017 Nov 15.
J Virol. 2017.
PMID: 28835501
Free PMC article.
Clinical Trial.
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Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosome.
Huang Y, Hidalgo-Bravo A, Zhang E, Cotton VE, Mendez-Bermudez A, Wig G, Medina-Calzada Z, Neumann R, Jeffreys AJ, Winney B, Wilson JF, Clark DA, Dyer MJ, Royle NJ.
Huang Y, et al.
Nucleic Acids Res. 2014 Jan;42(1):315-27. doi: 10.1093/nar/gkt840. Epub 2013 Sep 19.
Nucleic Acids Res. 2014.
PMID: 24057213
Free PMC article.
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HHV-8-unrelated primary effusion-like lymphoma associated with clonal loss of inherited chromosomally-integrated human herpesvirus-6A from the telomere of chromosome 19q.
Zhang E, Cotton VE, Hidalgo-Bravo A, Huang Y, Bell AJ, Jarrett RF, Wilkie GS, Davison AJ, Nacheva EP, Siebert R, Majid A, Kelpanides I, Jayne S, Dyer MJ, Royle NJ.
Zhang E, et al.
Sci Rep. 2016 Mar 7;6:22730. doi: 10.1038/srep22730.
Sci Rep. 2016.
PMID: 26947392
Free PMC article.
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