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Year | Number of Results |
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2008 | 1 |
2010 | 1 |
2012 | 2 |
2024 | 0 |
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Page 1
Differential oxidation of two thiophene-containing regioisomers to reactive metabolites by cytochrome P450 2C9.
Chem Res Toxicol. 2012 Apr 16;25(4):895-903. doi: 10.1021/tx200519d. Epub 2012 Mar 14.
Chem Res Toxicol. 2012.
PMID: 22329513
Free PMC article.
Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism.
Huang Q, Deshmukh RS, Ericksen SS, Tu Y, Szklarz GD.
Huang Q, et al.
Drug Metab Dispos. 2012 Dec;40(12):2324-31. doi: 10.1124/dmd.112.047308. Epub 2012 Sep 4.
Drug Metab Dispos. 2012.
PMID: 22949628
Free PMC article.
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Application of molecular modeling for prediction of substrate specificity in cytochrome P450 1A2 mutants.
Tu Y, Deshmukh R, Sivaneri M, Szklarz GD.
Tu Y, et al.
Drug Metab Dispos. 2008 Nov;36(11):2371-80. doi: 10.1124/dmd.108.022640. Epub 2008 Aug 14.
Drug Metab Dispos. 2008.
PMID: 18703643
Free PMC article.
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Significant increase in phenacetin oxidation on L382V substitution in human cytochrome P450 1A2.
Huang Q, Szklarz GD.
Huang Q, et al.
Drug Metab Dispos. 2010 Jul;38(7):1039-45. doi: 10.1124/dmd.109.030767. Epub 2010 Mar 24.
Drug Metab Dispos. 2010.
PMID: 20335269
Free PMC article.
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