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2012 1
2013 4
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28 results

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Page 1
Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms.
Faravelli G, Mondani V, Mangione PP, Raimondi S, Marchese L, Lavatelli F, Stoppini M, Corazza A, Canetti D, Verona G, Obici L, Taylor GW, Gillmore JD, Giorgetti S, Bellotti V. Faravelli G, et al. Front Mol Biosci. 2022 Feb 14;9:830006. doi: 10.3389/fmolb.2022.830006. eCollection 2022. Front Mol Biosci. 2022. PMID: 35237660 Free PMC article. Review.
Breakdown of supersaturation barrier links protein folding to amyloid formation.
Noji M, Samejima T, Yamaguchi K, So M, Yuzu K, Chatani E, Akazawa-Ogawa Y, Hagihara Y, Kawata Y, Ikenaka K, Mochizuki H, Kardos J, Otzen DE, Bellotti V, Buchner J, Goto Y. Noji M, et al. Commun Biol. 2021 Jan 26;4(1):120. doi: 10.1038/s42003-020-01641-6. Commun Biol. 2021. PMID: 33500517 Free PMC article.
Plasminogen activation triggers transthyretin amyloidogenesis in vitro.
Mangione PP, Verona G, Corazza A, Marcoux J, Canetti D, Giorgetti S, Raimondi S, Stoppini M, Esposito M, Relini A, Canale C, Valli M, Marchese L, Faravelli G, Obici L, Hawkins PN, Taylor GW, Gillmore JD, Pepys MB, Bellotti V. Mangione PP, et al. J Biol Chem. 2018 Sep 14;293(37):14192-14199. doi: 10.1074/jbc.RA118.003990. Epub 2018 Jul 17. J Biol Chem. 2018. PMID: 30018138 Free PMC article.
Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies.
Mangione PP, Mazza G, Gilbertson JA, Rendell NB, Canetti D, Giorgetti S, Frenguelli L, Curti M, Rezk T, Raimondi S, Pepys MB, Hawkins PN, Gillmore JD, Taylor GW, Pinzani M, Bellotti V. Mangione PP, et al. J Proteomics. 2017 Aug 8;165:113-118. doi: 10.1016/j.jprot.2017.06.016. Epub 2017 Jun 21. J Proteomics. 2017. PMID: 28647518 Free PMC article.
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis.
Marcoux J, Mangione PP, Porcari R, Degiacomi MT, Verona G, Taylor GW, Giorgetti S, Raimondi S, Sanglier-Cianférani S, Benesch JL, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Stoppini M, Robinson CV, Pepys MB, Bellotti V. Marcoux J, et al. EMBO Mol Med. 2015 Oct;7(10):1337-49. doi: 10.15252/emmm.201505357. EMBO Mol Med. 2015. PMID: 26286619 Free PMC article.
Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis.
Slamova I, Adib R, Ellmerich S, Golos MR, Gilbertson JA, Botcher N, Canetti D, Taylor GW, Rendell N, Tennent GA, Verona G, Porcari R, Mangione PP, Gillmore JD, Pepys MB, Bellotti V, Hawkins PN, Al-Shawi R, Simons JP. Slamova I, et al. Nat Commun. 2021 Dec 7;12(1):7112. doi: 10.1038/s41467-021-27416-z. Nat Commun. 2021. PMID: 34876572 Free PMC article.
28 results