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A rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelope glycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity in pseudotyping assays.
Kraus MH, Parrish NF, Shaw KS, Decker JM, Keele BF, Salazar-Gonzalez JF, Grayson T, McPherson DT, Ping LH, Anderson JA, Swanstrom R, Williamson C, Shaw GM, Hahn BH. Kraus MH, et al. Virology. 2010 Feb 20;397(2):346-57. doi: 10.1016/j.virol.2009.11.019. Epub 2009 Dec 8. Virology. 2010. PMID: 20003995 Free PMC article.