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UCP1 governs liver extracellular succinate and inflammatory pathogenesis.
Mills EL, Harmon C, Jedrychowski MP, Xiao H, Garrity R, Tran NV, Bradshaw GA, Fu A, Szpyt J, Reddy A, Prendeville H, Danial NN, Gygi SP, Lynch L, Chouchani ET. Mills EL, et al. Nat Metab. 2021 May;3(5):604-617. doi: 10.1038/s42255-021-00389-5. Epub 2021 May 17. Nat Metab. 2021. PMID: 34002097 Free PMC article. Review.
Redox regulation of macrophages.
Tran N, Mills EL. Tran N, et al. Redox Biol. 2024 Jun;72:103123. doi: 10.1016/j.redox.2024.103123. Epub 2024 Mar 12. Redox Biol. 2024. PMID: 38615489 Free PMC article. Review.
Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation.
Mills EL, Harmon C, Jedrychowski MP, Xiao H, Gruszczyk AV, Bradshaw GA, Tran N, Garrity R, Laznik-Bogoslavski D, Szpyt J, Prendeville H, Lynch L, Murphy MP, Gygi SP, Spiegelman BM, Chouchani ET. Mills EL, et al. Cell Metab. 2022 Jan 4;34(1):140-157.e8. doi: 10.1016/j.cmet.2021.11.003. Epub 2021 Dec 2. Cell Metab. 2022. PMID: 34861155 Free PMC article.
Career pathways, part 9.
Mills EL, Chouchani ET. Mills EL, et al. Nat Metab. 2022 Aug;4(8):961-962. doi: 10.1038/s42255-022-00624-7. Nat Metab. 2022. PMID: 35931883 Free PMC article.
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor.
Darabedian N, Ji W, Fan M, Lin S, Seo HS, Vinogradova EV, Yaron TM, Mills EL, Xiao H, Senkane K, Huntsman EM, Johnson JL, Che J, Cantley LC, Cravatt BF, Dhe-Paganon S, Stegmaier K, Zhang T, Gray NS, Chouchani ET. Darabedian N, et al. Nat Chem Biol. 2023 Jul;19(7):815-824. doi: 10.1038/s41589-023-01273-x. Epub 2023 Feb 23. Nat Chem Biol. 2023. PMID: 36823351 Free PMC article.