R01 AG030142/AG/NIA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2008	1
2010	1
2011	2
2012	2
2013	4
2014	4
2015	1
2016	2
2017	3
2018	1
2019	1
2021	1
2022	4
2024	1

1

APP mouse models for Alzheimer's disease preclinical studies.

Sasaguri H, Nilsson P, Hashimoto S, Nagata K, Saito T, De Strooper B, Hardy J, Vassar R, Winblad B, Saido TC. Sasaguri H, et al. EMBO J. 2017 Sep 1;36(17):2473-2487. doi: 10.15252/embj.201797397. Epub 2017 Aug 1. EMBO J. 2017. PMID: 28768718 Free PMC article. Review.

2

Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice.

Cuddy LK, Alia AO, Salvo MA, Chandra S, Grammatopoulos TN, Justman CJ, Lansbury PT Jr, Mazzulli JR, Vassar R. Cuddy LK, et al. Mol Neurodegener. 2022 Aug 20;17(1):54. doi: 10.1186/s13024-022-00561-9. Mol Neurodegener. 2022. PMID: 35987691 Free PMC article.

3

The secretases: enzymes with therapeutic potential in Alzheimer disease.

De Strooper B, Vassar R, Golde T. De Strooper B, et al. Nat Rev Neurol. 2010 Feb;6(2):99-107. doi: 10.1038/nrneurol.2009.218. Nat Rev Neurol. 2010. PMID: 20139999 Free PMC article. Review.

4

Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.

Yan R, Fan Q, Zhou J, Vassar R. Yan R, et al. Neurosci Biobehav Rev. 2016 Jun;65:326-40. doi: 10.1016/j.neubiorev.2016.03.025. Epub 2016 Apr 1. Neurosci Biobehav Rev. 2016. PMID: 27044452 Free PMC article. Review.

5

Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects.

Vassar R, Kuhn PH, Haass C, Kennedy ME, Rajendran L, Wong PC, Lichtenthaler SF. Vassar R, et al. J Neurochem. 2014 Jul;130(1):4-28. doi: 10.1111/jnc.12715. Epub 2014 Apr 19. J Neurochem. 2014. PMID: 24646365 Free PMC article. Review.

6

Loss of motor function in preclinical Alzheimer's disease.

Buchman AS, Bennett DA. Buchman AS, et al. Expert Rev Neurother. 2011 May;11(5):665-76. doi: 10.1586/ern.11.57. Expert Rev Neurother. 2011. PMID: 21539487 Free PMC article. Review.

7

Targeting the β secretase BACE1 for Alzheimer's disease therapy.

Yan R, Vassar R. Yan R, et al. Lancet Neurol. 2014 Mar;13(3):319-29. doi: 10.1016/S1474-4422(13)70276-X. Epub 2014 Feb 17. Lancet Neurol. 2014. PMID: 24556009 Free PMC article. Review.

8

Pregabalin Treatment does not Affect Amyloid Pathology in 5XFAD Mice.

Sadleir KR, Popovoic J, Zhu W, Reidel CT, Do H, Silverman RB, Vassar R. Sadleir KR, et al. Curr Alzheimer Res. 2021;18(4):283-297. doi: 10.2174/1567205018666210713125333. Curr Alzheimer Res. 2021. PMID: 34259145 Free PMC article.

9

A conserved annexin A6-mediated membrane repair mechanism in muscle, heart, and nerve.

Demonbreun AR, Bogdanovic E, Vaught LA, Reiser NL, Fallon KS, Long AM, Oosterbaan CC, Hadhazy M, Page PG, Joseph PRB, Cowen G, Telenson AM, Khatri A, Sadleir KR, Vassar R, McNally EM. Demonbreun AR, et al. JCI Insight. 2022 Jul 22;7(14):e158107. doi: 10.1172/jci.insight.158107. JCI Insight. 2022. PMID: 35866481 Free PMC article.

10

The contribution of activated astrocytes to Aβ production: implications for Alzheimer's disease pathogenesis.

Zhao J, O'Connor T, Vassar R. Zhao J, et al. J Neuroinflammation. 2011 Nov 2;8:150. doi: 10.1186/1742-2094-8-150. J Neuroinflammation. 2011. PMID: 22047170 Free PMC article.

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