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A cardiovascular drug rescues mice from lethal sepsis by selectively attenuating a late-acting proinflammatory mediator, high mobility group box 1.
J Immunol. 2007 Mar 15;178(6):3856-64. doi: 10.4049/jimmunol.178.6.3856.
J Immunol. 2007.
PMID: 17339485
Free PMC article.
The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages.
Tang D, Kang R, Xiao W, Wang H, Calderwood SK, Xiao X.
Tang D, et al.
J Immunol. 2007 Jul 15;179(2):1236-44. doi: 10.4049/jimmunol.179.2.1236.
J Immunol. 2007.
PMID: 17617616
Free PMC article.
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Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release.
Tang D, Kang R, Xiao W, Jiang L, Liu M, Shi Y, Wang K, Wang H, Xiao X.
Tang D, et al.
J Immunol. 2007 Jun 1;178(11):7376-84. doi: 10.4049/jimmunol.178.11.7376.
J Immunol. 2007.
PMID: 17513788
Free PMC article.
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