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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 2
2009 2
2011 4
2012 5
2013 4
2014 5
2015 1
2016 3
2017 4
2018 4
2019 6
2020 2
2021 5
2022 3
2024 0

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Page 1
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1.
Shin HR, Citron YR, Wang L, Tribouillard L, Goul CS, Stipp R, Sugasawa Y, Jain A, Samson N, Lim CY, Davis OB, Castaneda-Carpio D, Qian M, Nomura DK, Perera RM, Park E, Covey DF, Laplante M, Evers AS, Zoncu R. Shin HR, et al. Science. 2022 Sep 16;377(6612):1290-1298. doi: 10.1126/science.abg6621. Epub 2022 Aug 25. Science. 2022. PMID: 36007018 Free PMC article.
Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.
Castellano BM, Thelen AM, Moldavski O, Feltes M, van der Welle RE, Mydock-McGrane L, Jiang X, van Eijkeren RJ, Davis OB, Louie SM, Perera RM, Covey DF, Nomura DK, Ory DS, Zoncu R. Castellano BM, et al. Science. 2017 Mar 24;355(6331):1306-1311. doi: 10.1126/science.aag1417. Science. 2017. PMID: 28336668 Free PMC article.
Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.
Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I. Wang X, et al. Cell Metab. 2020 May 5;31(5):969-986.e7. doi: 10.1016/j.cmet.2020.03.010. Epub 2020 Apr 6. Cell Metab. 2020. PMID: 32259482 Free PMC article.
Side-chain oxysterols: from cells to membranes to molecules.
Olsen BN, Schlesinger PH, Ory DS, Baker NA. Olsen BN, et al. Biochim Biophys Acta. 2012 Feb;1818(2):330-6. doi: 10.1016/j.bbamem.2011.06.014. Epub 2011 Jul 1. Biochim Biophys Acta. 2012. PMID: 21745458 Free PMC article. Review.
Oxysterols as non-genomic regulators of cholesterol homeostasis.
Bielska AA, Schlesinger P, Covey DF, Ory DS. Bielska AA, et al. Trends Endocrinol Metab. 2012 Mar;23(3):99-106. doi: 10.1016/j.tem.2011.12.002. Epub 2012 Jan 11. Trends Endocrinol Metab. 2012. PMID: 22244444 Free PMC article.
47 results