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Page 1
The DcpS inhibitor RG3039 improves motor function in SMA mice.
Van Meerbeke JP, Gibbs RM, Plasterer HL, Miao W, Feng Z, Lin MY, Rucki AA, Wee CD, Xia B, Sharma S, Jacques V, Li DK, Pellizzoni L, Rusche JR, Ko CP, Sumner CJ. Van Meerbeke JP, et al. Hum Mol Genet. 2013 Oct 15;22(20):4074-83. doi: 10.1093/hmg/ddt257. Epub 2013 May 31. Hum Mol Genet. 2013. PMID: 23727836 Free PMC article.
Deletion of Ripk3 Prevents Motor Neuron Death In Vitro but not In Vivo.
Dermentzaki G, Politi KA, Lu L, Mishra V, Pérez-Torres EJ, Sosunov AA, McKhann GM 2nd, Lotti F, Shneider NA, Przedborski S. Dermentzaki G, et al. eNeuro. 2019 Feb 19;6(1):ENEURO.0308-18.2018. doi: 10.1523/ENEURO.0308-18.2018. eCollection 2019 Jan-Feb. eNeuro. 2019. PMID: 30815534 Free PMC article.
Pharmacokinetics, pharmacodynamics, and efficacy of a small-molecule SMN2 splicing modifier in mouse models of spinal muscular atrophy.
Zhao X, Feng Z, Ling KK, Mollin A, Sheedy J, Yeh S, Petruska J, Narasimhan J, Dakka A, Welch EM, Karp G, Chen KS, Metzger F, Ratni H, Lotti F, Tisdale S, Naryshkin NA, Pellizzoni L, Paushkin S, Ko CP, Weetall M. Zhao X, et al. Hum Mol Genet. 2016 May 15;25(10):1885-1899. doi: 10.1093/hmg/ddw062. Epub 2016 Feb 29. Hum Mol Genet. 2016. PMID: 26931466 Free PMC article.
15 results