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Importance of Genetic Studies of Cardiometabolic Disease in Diverse Populations.
Fernández-Rhodes L, Young KL, Lilly AG, Raffield LM, Highland HM, Wojcik GL, Agler C, Love SM, Okello S, Petty LE, Graff M, Below JE, Divaris K, North KE. Fernández-Rhodes L, et al. Circ Res. 2020 Jun 5;126(12):1816-1840. doi: 10.1161/CIRCRESAHA.120.315893. Epub 2020 Jun 4. Circ Res. 2020. PMID: 32496918 Free PMC article. Review.
Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants.
Young KL, Fisher V, Deng X, Brody JA, Graff M, Lim E, Lin BM, Xu H, Amin N, An P, Aslibekyan S, Fohner AE, Hidalgo B, Lenzini P, Kraaij R, Medina-Gomez C, Prokić I, Rivadeneira F, Sitlani C, Tao R, van Rooij J, Zhang D, Broome JG, Buth EJ, Heavner BD, Jain D, Smith AV, Barnes K, Boorgula MP, Chavan S, Darbar D, De Andrade M, Guo X, Haessler J, Irvin MR, Kalyani RR, Kardia SLR, Kooperberg C, Kim W, Mathias RA, McDonald ML, Mitchell BD, Peyser PA, Regan EA, Redline S, Reiner AP, Rich SS, Rotter JI, Smith JA, Weiss S, Wiggins KL, Yanek LR, Arnett D, Heard-Costa NL, Leal S, Lin D, McKnight B, Province M, van Duijn CM, North KE, Cupples LA, Liu CT. Young KL, et al. HGG Adv. 2022 Nov 25;4(1):100163. doi: 10.1016/j.xhgg.2022.100163. eCollection 2023 Jan 12. HGG Adv. 2022. PMID: 36568030 Free PMC article.
Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits.
Highland HM, Wojcik GL, Graff M, Nishimura KK, Hodonsky CJ, Baldassari AR, Cote AC, Cheng I, Gignoux CR, Tao R, Li Y, Boerwinkle E, Fornage M, Haessler J, Hindorff LA, Hu Y, Justice AE, Lin BM, Lin D, Stram DO, Haiman CA, Kooperberg C, Le Marchand L, Matise TC, Kenny EE, Carlson CS, Stahl EA, Avery CL, North KE, Ambite JL, Buyske S, Loos RJ, Peters U, Young KL, Bien SA, Huckins LM. Highland HM, et al. Am J Hum Genet. 2022 Apr 7;109(4):669-679. doi: 10.1016/j.ajhg.2022.02.013. Epub 2022 Mar 8. Am J Hum Genet. 2022. PMID: 35263625 Free PMC article.