R29 HL054889/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1998	3
1999	2
2000	2
2001	1
2002	4
2003	1
2004	2
2006	2
2011	1
2024	0

1

Deoxyadenosine bisphosphate derivatives as potent antagonists at P2Y1 receptors.

Camaioni E, Boyer JL, Mohanram A, Harden TK, Jacobson KA. Camaioni E, et al. J Med Chem. 1998 Jan 15;41(2):183-90. doi: 10.1021/jm970433l. J Med Chem. 1998. PMID: 9457242 Free PMC article.

2

Synthesis and Structure-Activity Relationships of Pyridoxal-6-arylazo-5'-phosphate and Phosphonate Derivatives as P2 Receptor Antagonists.

Kim YC, Camaioni E, Ziganshin AU, Ji XD, King BF, Wildman SS, Rychkov A, Yoburn J, Kim H, Mohanram A, Harden TK, Boyer JL, Burnstock G, Jacobson KA. Kim YC, et al. Drug Dev Res. 1998 Oct 1;45(2):52-66. doi: 10.1002/(SICI)1098-2299(199810)45:2<52::AID-DDR2>3.0.CO;2-V. Drug Dev Res. 1998. PMID: 22922976 Free PMC article.

3

Acyclic analogues of deoxyadenosine 3',5'-bisphosphates as P2Y(1) receptor antagonists.

Kim YC, Gallo-Rodriguez C, Jang SY, Nandanan E, Adams M, Harden TK, Boyer JL, Jacobson KA. Kim YC, et al. J Med Chem. 2000 Feb 24;43(4):746-55. doi: 10.1021/jm9905211. J Med Chem. 2000. PMID: 10691699 Free PMC article.

4

Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists.

Nandanan E, Camaioni E, Jang SY, Kim YC, Cristalli G, Herdewijn P, Secrist JA 3rd, Tiwari KN, Mohanram A, Harden TK, Boyer JL, Jacobson KA. Nandanan E, et al. J Med Chem. 1999 May 6;42(9):1625-38. doi: 10.1021/jm980657j. J Med Chem. 1999. PMID: 10229631 Free PMC article.

5

Ser352 and Ser354 in the carboxyl terminus of the human P2Y(1) receptor are required for agonist-promoted phosphorylation and internalization in MDCK cells.

Qi AD, Houston-Cohen D, Naruszewicz I, Harden TK, Nicholas RA. Qi AD, et al. Br J Pharmacol. 2011 Mar;162(6):1304-13. doi: 10.1111/j.1476-5381.2010.01135.x. Br J Pharmacol. 2011. PMID: 21108629 Free PMC article.

6

Synthesis, biological activity, and molecular modeling of ribose-modified deoxyadenosine bisphosphate analogues as P2Y(1) receptor ligands.

Nandanan E, Jang SY, Moro S, Kim HO, Siddiqui MA, Russ P, Marquez VE, Busson R, Herdewijn P, Harden TK, Boyer JL, Jacobson KA. Nandanan E, et al. J Med Chem. 2000 Mar 9;43(5):829-42. doi: 10.1021/jm990249v. J Med Chem. 2000. PMID: 10715151 Free PMC article.

7

Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors.

Kim YC, Brown SG, Harden TK, Boyer JL, Dubyak G, King BF, Burnstock G, Jacobson KA. Kim YC, et al. J Med Chem. 2001 Feb 1;44(3):340-9. doi: 10.1021/jm9904203. J Med Chem. 2001. PMID: 11462975 Free PMC article.

8

Delineation of ligand binding and receptor signaling activities of purified P2Y receptors reconstituted with heterotrimeric G proteins.

Bodor ET, Waldo GL, Blaesius R, Harden TK. Bodor ET, et al. Purinergic Signal. 2004 Dec;1(1):43-9. doi: 10.1007/s11302-004-4748-1. Purinergic Signal. 2004. PMID: 18404399 Free PMC article.

9

Functional expression of a cDNA encoding a human ecto-ATPase.

Mateo J, Harden TK, Boyer JL. Mateo J, et al. Br J Pharmacol. 1999 Sep;128(2):396-402. doi: 10.1038/sj.bjp.0702805. Br J Pharmacol. 1999. PMID: 10510450 Free PMC article.

10

2-Chloro N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate is a selective high affinity P2Y(1) receptor antagonist.

Boyer JL, Adams M, Ravi RG, Jacobson KA, Harden TK. Boyer JL, et al. Br J Pharmacol. 2002 Apr;135(8):2004-10. doi: 10.1038/sj.bjp.0704673. Br J Pharmacol. 2002. PMID: 11959804 Free PMC article.

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