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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2018 4
2019 6
2020 9
2021 8
2022 6
2023 4
2024 2

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39 results

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Page 1
How many rare diseases are there?
Haendel M, Vasilevsky N, Unni D, Bologa C, Harris N, Rehm H, Hamosh A, Baynam G, Groza T, McMurry J, Dawkins H, Rath A, Thaxton C, Bocci G, Joachimiak MP, Köhler S, Robinson PN, Mungall C, Oprea TI. Haendel M, et al. Nat Rev Drug Discov. 2020 Feb;19(2):77-78. doi: 10.1038/d41573-019-00180-y. Nat Rev Drug Discov. 2020. PMID: 32020066 Free PMC article.
QSAR without borders.
Muratov EN, Bajorath J, Sheridan RP, Tetko IV, Filimonov D, Poroikov V, Oprea TI, Baskin II, Varnek A, Roitberg A, Isayev O, Curtarolo S, Fourches D, Cohen Y, Aspuru-Guzik A, Winkler DA, Agrafiotis D, Cherkasov A, Tropsha A. Muratov EN, et al. Chem Soc Rev. 2020 Jun 7;49(11):3525-3564. doi: 10.1039/d0cs00098a. Epub 2020 May 1. Chem Soc Rev. 2020. PMID: 32356548 Free PMC article. Review.
Off-Patent Drug Repositioning.
Avram S, Curpan R, Halip L, Bora A, Oprea TI. Avram S, et al. J Chem Inf Model. 2020 Dec 28;60(12):5746-5753. doi: 10.1021/acs.jcim.0c00826. Epub 2020 Sep 15. J Chem Inf Model. 2020. PMID: 32877182
DrugCentral 2018: an update.
Ursu O, Holmes J, Bologa CG, Yang JJ, Mathias SL, Stathias V, Nguyen DT, Schürer S, Oprea T. Ursu O, et al. Nucleic Acids Res. 2019 Jan 8;47(D1):D963-D970. doi: 10.1093/nar/gky963. Nucleic Acids Res. 2019. PMID: 30371892 Free PMC article.
TIGA: target illumination GWAS analytics.
Yang JJ, Grissa D, Lambert CG, Bologa CG, Mathias SL, Waller A, Wild DJ, Jensen LJ, Oprea TI. Yang JJ, et al. Bioinformatics. 2021 Nov 5;37(21):3865-3873. doi: 10.1093/bioinformatics/btab427. Bioinformatics. 2021. PMID: 34086846 Free PMC article.
AlphaFold illuminates half of the dark human proteins.
Binder JL, Berendzen J, Stevens AO, He Y, Wang J, Dokholyan NV, Oprea TI. Binder JL, et al. Curr Opin Struct Biol. 2022 Jun;74:102372. doi: 10.1016/j.sbi.2022.102372. Epub 2022 Apr 16. Curr Opin Struct Biol. 2022. PMID: 35439658 Free PMC article. Review.
Unexplored therapeutic opportunities in the human genome.
Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G. Oprea TI, et al. Nat Rev Drug Discov. 2018 May;17(5):317-332. doi: 10.1038/nrd.2018.14. Epub 2018 Mar 23. Nat Rev Drug Discov. 2018. PMID: 29472638 Free PMC article. Review.
Exploring DrugCentral: from molecular structures to clinical effects.
Halip L, Avram S, Curpan R, Borota A, Bora A, Bologa C, Oprea TI. Halip L, et al. J Comput Aided Mol Des. 2023 Dec;37(12):681-694. doi: 10.1007/s10822-023-00529-x. Epub 2023 Sep 14. J Comput Aided Mol Des. 2023. PMID: 37707619 Free PMC article. Review.
39 results