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Correlation of CGS 19755 neuroprotection against in vitro excitotoxicity and focal cerebral ischemia.
Pérez-Pinzón MA, Maier CM, Yoon EJ, Sun GH, Giffard RG, Steinberg GK. Pérez-Pinzón MA, et al. J Cereb Blood Flow Metab. 1995 Sep;15(5):865-76. doi: 10.1038/jcbfm.1995.108. J Cereb Blood Flow Metab. 1995. PMID: 7673380
CSF and brain levels of CGS 19755 were 12 microM and 5 microM, respectively, at 1 h, 6 microM and 5 microM at 2 h, and 13 microM and 7 microM at 4 h. ...
CSF and brain levels of CGS 19755 were 12 microM and 5 microM, respectively, at 1 h, 6 microM and 5 microM at 2 h, and 13 microM and …
Neuroprotection by the N-methyl-D-aspartate receptor antagonist CGP 40116: in vivo and in vitro studies.
Maier CM, Sun GH, Kunis DM, Giffard RG, Steinberg GK. Maier CM, et al. J Neurochem. 1995 Aug;65(2):652-9. doi: 10.1046/j.1471-4159.1995.65020652.x. J Neurochem. 1995. PMID: 7616221

CGP 40116 decreased cortical ischemic neuronal damage by 74 and 77% (control, 37.8 +/- 13.1%; CGP 20 mg/kg, 9.9 +/- 3.6%; CGP 40 mg/kg, 8.7 +/- 3.7%; p < 0.01) and reduced cortical ischemic edema by 52 and 35% (control, 42.3 +/- 10.4%; CGP 20 mg/kg, 20.1 +/- 6.7%

…
CGP 40116 decreased cortical ischemic neuronal damage by 74 and 77% (control, 37.8 +/- 13.1%; CGP 20 mg/kg, 9.9 +/- 3.6%; CGP 40 mg/k …